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Molindone
go.drugbank.com/drugs/DB01618ApprovedMolindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. … An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder.
Molybdenum
go.drugbank.com/drugs/DB11137ApprovedInvestigationalMolybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. … When complexed with Technetium Tc 99m, molybdenum is used as a radiopharmaceutical agent in diagonistic procedures.
Mixtures: Extra Once A Day, Maximum Once A DayINCB13739
go.drugbank.com/drugs/DB05064InvestigationalINCB13739 is developed as a new treatment for type 2 diabetes. … It is an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be critical to the development of type 2 diabetes
Elafin
go.drugbank.com/drugs/DB05161InvestigationalThe excellent tolerability of Elafin in human subjects was demonstrated in a Phase I clinical single dose escalating study. … Elafin is a human protein that is produced naturally in the skin, lung and breast, protecting the respective tissue from destruction by the immune system.
Pinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalPinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. … Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCipepofol
go.drugbank.com/drugs/DB16295ApprovedInvestigationalCipepofol is an intravenous general anesthetic of the alkylphenol class, supplied as a sterile lipid emulsion, which is thought to act by positively modulating the inhibitory function of GABA at ligand-gated … GABA-A receptors, similar to the previously approved [propofol].
Balsalazide
go.drugbank.com/drugs/DB01014ApprovedMesalazine is also known as 5-aminosalicylic acid, or 5-ASA. … Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
Synonyms: (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acidAcellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalApproved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral
Ularitide
go.drugbank.com/drugs/DB05034InvestigationalUlaritide is currently in Phase 2 development as a potential treatment for patients with acute decompensated heart failure (ADHF). … When injected into the blood, ularitide appears to cause diuresis (urine output) and natriuresis (sodium excretion), as well as vasodilation.
Teprotumumab
go.drugbank.com/drugs/DB06343ApprovedInvestigationalTeprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. … multiple invasive surgeries - teprotumumab is the first drug ever approved for the treatment of TED and therefore represents a significant step forward in the treatment this disease.