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Esmolol
go.drugbank.com/drugs/DB00187ApprovedInvestigationalWithdrawnEsmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate of heart contractions.
Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate, 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl esterTransient receptor potential cation channel subfamily V member 5
go.drugbank.com/bio_entities/BE0005112TransporterHumansConstitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubu...
Polypeptides: Transient receptor potential cation channel subfamily V member 5Solute carrier family 2, facilitated glucose transporter member 5
go.drugbank.com/bio_entities/BE0005216TransporterHumansFunctions as a fructose transporter that has only low activity with other monosaccharides (PubMed:16186102, PubMed:17710649, PubMed:28083649, PubMed:29548810, PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low effici...
Polypeptides: Solute carrier family 2, facilitated glucose transporter member 5Synonyms: GLUT-5, Glucose transporter type 5, small intestineNadolol
go.drugbank.com/drugs/DB01203ApprovedInvestigational[L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and … Nadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure.
Mixtures: CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MG, Corzide Tab W Nadolol 80mgCategories: MATE 1 Substrates, MATE 2 SubstratesDimethicone
go.drugbank.com/drugs/DB11074ApprovedInvestigationalIt is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. … Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants.
Mixtures: Medpride En Shield, PANKREOFLAT 170/310 MG GRANÜL (22x2 g poşet)Categories: Compounds used in a research, industrial, or household settingBenzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalThe generation of structure-activity relationships proved that benztropine derivatives with the presence of a chlorine substituent in the para position in one of the phenyl rings produces an increased … It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970.
Synonyms: benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether, 3α-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octaneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigational[L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection. … [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006.
Synonyms: N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido)propyl)carbamateMixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET, VIRONTAR N COMPRIMIDOS RECUBIERTOSCalcium carbonate
go.drugbank.com/drugs/DB06724ApprovedInvestigationalCalcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. … Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia.
Mixtures: MAGCAR 680 MG+80 MG/5 ML SÜSPANSİYON, 100 ML, RENNIE 680 MG/80 MG/5 ML SUSPANSIYON, 100 MLCategories: ascorbic acid (vit C) and calciumPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. … It is currently not approved for use in the United States.
Synonyms: N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine, N-(3-Dimethylaminopropyl)phenothiazineCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsTenoxicam
go.drugbank.com/drugs/DB00469ApprovedInvestigationalTenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesProducts: ZOLIMIN® INYECTABLE 20 MG., TİCOTEN 20 MG/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET