Search
Carboprost tromethamine
go.drugbank.com/drugs/DB00429ApprovedInvestigationalA nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Categories: Prostaglandins F, SyntheticSynonyms: 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium (5Z,9α,11β,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oate, 15(S)-15-methyl-PGF2α tromethamine saltImdevimab
go.drugbank.com/drugs/DB15940ApprovedInvestigational[L23539] This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … Imdevimab is a monoclonal antibody combined with [casirivimab] in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19.
Carob
go.drugbank.com/drugs/DB10852ApprovedCarob allergenic extract is used in allergenic testing.
Categories: Compounds used in a research, industrial, or household settingFosphenytoin
go.drugbank.com/drugs/DB01320ApprovedInvestigationalFosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: (3-Phosphoryloxymethyl)phenytoinDavesomeran
go.drugbank.com/drugs/DB17091ApprovedInvestigationalDavesomeran is a mRNA vaccine used in conjunction with [elasomeran] as part of the Moderna Bivalent COVID-19 vaccine. … [L43882] In October 22nd 2022, the FDA approved the Moderna Bivalent Vaccine as a booster in patients 6 years or older, administered at least 2 months after completion of primary vaccination or receipt
Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Sertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnIt is a phenylindole derivative used in the treatment of schizophrenia. … It was first marketed in 1996 in several European countries before being withdrawn two years later because of numerous cardiac adverse effects.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-onePrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Mixtures: PREFOX-T®, CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERILCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesToremifene
go.drugbank.com/drugs/DB00539ApprovedInvestigationalToremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to treat estrogen receptor positive breast cancer. … [A256928] Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone tissue and it has weak estrogenic effects on uterine tissue, however
Mixtures: FLOBACT - D, FLOBACT - DCategories: P-glycoprotein inhibitors, P-glycoprotein substratesAminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnIn biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. … Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazoloneAmitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]
Mixtures: โพลีบอน 4-10, Etrafon 2 10Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index