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Cresol
go.drugbank.com/drugs/DB11143ApprovedAt concentrations normally found in the environment however, cresols do not pose any significant risk for the general population. … Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal pain, and/or vomiting.
Rilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationalRilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome (FCAS)
Categories: Receptors, Interleukin-1 Type I, Interleukin-1 BlockersSynonyms: IL-1 TRAP, IL-1-TRAPPyrimidine Metabolism
smpdb.ca/view/SMP0000046MetabolicPyrimidine catabolism ultimately results in the formation of the waste products of urea, H2O, and CO2. … A group of heterocyclic aromatic organic compound, pyrimidines are similar in structure to benzene and pyridine and count the nucleic acids cytosine, thymine, and uracil as structural derivatives.
beta-Ureidopropionase Deficiency
smpdb.ca/view/SMP0000172DiseaseA deficiency in this enzyme results in accumulation of N-carbamyl-beta-amino acids. Symptoms include hypotonia, dystonic movements, scoliosis, microcephaly, and severe developmental delay. … Beta-ureidopropionase deficiency (Beta Alanine-Synthase Deficiency, UPB1, BUP1) is an autosomal recessive disease caused by mutations in the UPB1 gene which codes for beta-ureidopropionase.
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
smpdb.ca/view/SMP0000202DiseaseMNGIE causes accumulation of thymidine and deoxyuridine in the urine. … Myoneurogastrointestinal encephalopathy, or mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE), is a multisystem disorder caused by mutations in the gene encoding thymidine phosphorylase
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
smpdb.ca/view/SMP0125720DiseaseMNGIE causes accumulation of thymidine and deoxyuridine in the urine. … Myoneurogastrointestinal encephalopathy, or mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE), is a multisystem disorder caused by mutations in the gene encoding thymidine phosphorylase
UMP Synthase Deficiency (Orotic Aciduria)
smpdb.ca/view/SMP0000219DiseaseThis disease is characterized by a very large accumulation of orotic acid in the urine, occasionally causing urinary obstruction.
beta-Ureidopropionase Deficiency
smpdb.ca/view/SMP0125716DiseaseA deficiency in this enzyme results in accumulation of N-carbamyl-beta-amino acids. Symptoms include hypotonia, dystonic movements, scoliosis, microcephaly, and severe developmental delay. … Beta-ureidopropionase deficiency (Beta Alanine-Synthase Deficiency, UPB1, BUP1) is an autosomal recessive disease caused by mutations in the UPB1 gene which codes for beta-ureidopropionase.
UMP Synthase Deficiency (Orotic Aciduria)
smpdb.ca/view/SMP0125717DiseaseThis disease is characterized by a very large accumulation of orotic acid in the urine, occasionally causing urinary obstruction.
Corticorelin ovine triflutate
go.drugbank.com/drugs/DB09067ApprovedIt is used as a diagnostic agent to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion. … If corticorelin injection results in an increase of plasma ACTH and cortisol, the patient is diagnosed with Cushing's disease.
Synonyms: Sheep corticotropin-releasing factor (1-41)