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Displaying results 311 - 320 of 10000 in total
  1. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.

    Mixtures: CLORURO DE POTASIO 20 MEQ EN SODIO CLORURO 0.9 % POR 100 ML, CLORURO DE POTASIO 20 MEQ EN CLORURO DE SODIO 0.9% SOLUCIÓN INYECTABLE USP 500 MLProducts: CLORURO DE SODIO AL 0.9% EN AGUA INYECTABLE, CLORURO DE SODIO AL 0.9% EN AGUA INYECTABLE BAXTER
  2. Drug

    Brivaracetam

    go.drugbank.com/drugs/DB05541
    ApprovedInvestigational

    Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184]. … It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 [L760].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: BRIVIACT 10 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET, BRIVIACT 50 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET
  3. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243] … It binds to mineralocorticoid receptors and functions as aldosterone antagonists.[A178192] It promotes sodium and water excretion and potassium retention.

    Mixtures: SEMİTONE 50/20 MG FILM TABLET, 10 ADET, SEMİTONE 100/20 MG FILM TABLET, 10 ADETCategories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  4. Drug

    Sulpiride

    go.drugbank.com/drugs/DB00391
    ApprovedWithdrawn

    [A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. … [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in individual European countries.[L24679]

    Synonyms: N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide, 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamideCategories: MATE 2 Substrates
  5. Drug

    Magrolimab

    go.drugbank.com/drugs/DB16225
    Investigational

    Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).

    Synonyms: Immunoglobulin g4-kappa, anti-(homo sapiens cd47 (integrin associated protein, iap, mer6, oa3)), monoclonal antibodygamma4 heavy chain (1-444) (vh (homo sapiens ighv1-3*01 (87.8%)-(ighd)-ighj4*01 (100%, )) (8.8.10) (1-117)-homo sapiens ighg4*01 (ch1 (118-2
  6. Drug

    Ciprofloxacin

    go.drugbank.com/drugs/DB00537
    ApprovedInvestigational

    [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463] … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.

    Synonyms: 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acidMixtures: ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADET, ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET
  7. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950.

    Synonyms: N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate, 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)Mixtures: Arlevert 20 mg/40 mg Tabletten
  8. Drug

    Methotrexate

    go.drugbank.com/drugs/DB00563
    ApprovedInvestigational

    [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients … [L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198]

    Synonyms: 4-amino-N(10)-methylpteroylglutamic acid, 4-amino-10-methylfolic acidCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 Substrates
  9. Drug

    Cefpodoxime

    go.drugbank.com/drugs/DB01416
    ApprovedInvestigationalVet approved

    Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria.

    Mixtures: TEXEF PLUS 100/62.5 MG FİLM KAPLI TABLET, 20 ADET, TEXEF PLUS 50 MG/62.5 MG GRANÜL İÇEREN SAŞE, 20 ADETCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Bismuth subcitrate potassium

    go.drugbank.com/drugs/DB09275
    ApprovedInvestigational

    A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).

    Mixtures: KATACOLD 120 MG + 3.75 MG+ l MG /5 ML PEDIYATRIK ŞURUP, 100 ML, Pylera 140 mg/125 mg/125 mg HartkapselnProducts: NOTUSS 50 MG SR TABLET, 20 ADET, KREVAL SR 50 MG FİLM KAPLI TABLET , 20 ADET