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Acute Renal Failure (ARF)
go.drugbank.com/conditions/DBCOND0081526Drugs: MannitolSynonyms: Pre-renal acute kidney injury, Pre-renal acute kidney injury (disorder)Aloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalAloe vera, or _Aloe barbadensis miller_, is the most common species of Aloe that is cultivated for agricultural and medical purposes. … Common active polysaccharides include glucomannans, polymannose, and acemannan, or b-(1–4)-acetylated polymannose [A32475].
Mixtures: Alcortin A, Alcortin AProducts: Secret No 1Lomitapide
go.drugbank.com/drugs/DB08827Approved[A275444, A7367] It was developed to address the significant unmet medical need in patients with homozygous familial hypercholesterolemia (HoFH)—an ultra-rare and life-threatening genetic disorder characterized … by extremely high levels of low-density lipoprotein cholesterol (LDL-C) and premature atherosclerotic cardiovascular disease.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A InhibitorsSynonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDEExemestane
go.drugbank.com/drugs/DB00990ApprovedInvestigationalExemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 6-methyleneandrosta-1,4-diene-3,17-dioneCPD 923
go.drugbank.com/drugs/DB05856ExperimentalCPD 923 (N-butylgalactonorjirimycin) is an iminosugar and an analogue of ZavescaTM. It shows efficacy in vivo studies, as well as a favourable pre-clinical tolerability profile.
Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10794ApprovedInvestigationalWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated), Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strainMixtures: Medical Provider Single Use EZ Flu Shot Fluzone 2016-2017Vilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigationalwith the (R)-configuration. … [A259966] Vilanterol's pharmacological effect is attributable to stimulation of intracellular adenylyl cyclase which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate
Mixtures: Anoro Ellipta 62.5/25 micrograms inhalation powder, pre-dispensed, Relvar Ellipta 100/25 micrograms inhalation powder, pre-dispensedCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesInfluenza B virus B/Darwin/7/2019 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB15709ApprovedWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza B virus B/Darwin/7/2019 antigen (MDCK cell derived, propiolactone inactivated)Mixtures: Flucelvax Quadrivalent (pre-filled Syringe), Flucelvax Quadrivalent (pre-filled Syringe)