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Methimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigational[L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and is the active metabolite of the … options such as surgery or radioactive iodine therapy are inappropriate.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsProducts: PERİZOL 10 MG FİLM KAPLI TABLET, 50 ADET, PERİZOL 10 MG FİLM KAPLI TABLET, 100 ADETLevobupivacaine
go.drugbank.com/drugs/DB01002ApprovedInvestigationalWithdrawnLevobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: CHIROCAINE 50 MG/10 ML INF. ICIN KONS. COZELTI ICEREN 10ML X 10 AMPUL, CHIROCAINE 25 MG/10 ML INF. ICIN KONS. COZELTI ICEREN 10ML X 10 AMPULIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: NOBENITRAT 10 MG TABLET, 50 ADET, ISORDIL 10 MG TABLET, 50 ADETHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalAccording to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first anti-cancer vaccine. … Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B.
Products: HEPATECT CP 500 IU 10 ML FLAKON, Hepatect CP 50 I.E./ml InfusionslösungInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalMarketed as the brand name product NovoRapid, insulin aspart begins to exert its effects within 15 minutes of subcutaneous administration, while peak levels occur 30 to 90 minutes after administration. … Due to its duration of action of around 5 hours, NovoRapid is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from
Mixtures: NOVOMIX 30 FLEXPEN INJECTION 100 u/ml, NOVOMIX 30 FLEXPEN INJECTION 100 u/mlCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalIron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
Mixtures: Myferon 150 Forte, Bal-Care DHAProducts: VELTIFER 100 MG/5 ML ORAL ÇÖZELTİ, 10 ADET, FERINT 100 MG/5 ML IV AMPUL ,AMPUL, 5 ADETMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedIt has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, DULAMON 100 MCG/5 MCG BASINÇLI İNHALASYON, SÜSPANSİYON, 60 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAllopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalIt was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942].
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: ALLOPIN 300 MG TABLET, 50 ADET, ÜRİKOLIZ 300 MG TABLET, 50 ADETNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigational[L8453,L8459] It was first approved for use in the United States in 2014. … such is used as a first-line treatment following diagnosis to slow down the progressive loss of lung function.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nintedanib Capsules, 100 mg and 150 mg, OFEV 100 MG YUMUSAK KAPSUL, 60 ADETFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalIt was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: REVOXIN 100 MG FILM TABLET, 30 ADET, FAVERIN 100 MG