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Ixazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigational[A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016. … [A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US.
Methysergide
go.drugbank.com/drugs/DB00247ApprovedWithdrawnMethysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome. … An ergot derivative that is a congener of lysergic acid diethylamide.
Synonyms: (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide, N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamideLevobupivacaine
go.drugbank.com/drugs/DB01002ApprovedInvestigationalWithdrawnto an anesthetic. … adults; and infiltration analgesia in children.
Coagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedRecombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric patients with congenital factor IX deficiency (Hemophilia B). … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell
Sunvozertinib
go.drugbank.com/drugs/DB18925Investigational[A274143] Sunvozertinib was granted accelerated approval in the US on July 2, 2025 for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor … Sunvozertinib is an irreversible and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor.
Synonyms: 2-Propenamide, N-[5-[[4-[[5-chloro-4-fluoro-2-(1-hydroxy-1- methylethyl)phenyl]amino]-2-pyrimidinyl]amino]-2-[(3R)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl]-, N-{5-[(4-{[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino}pyrimidin-2-yl)amino]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl}prop-2-enamideClomethiazole
go.drugbank.com/drugs/DB06470InvestigationalIt is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. … It is also used for the management of agitation, restlessness, short-term insomnia and Parkinson's disease in the elderly.
Categories: Compounds used in a research, industrial, or household settingButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedIt is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. … It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring.
Mixtures: OREN COMPOSITUM TABLETAS, OREN COMPOSITIUM TABLETASSynonyms: N-butylscopolammonium, N-butylscopolammonium ionCarbetocin
go.drugbank.com/drugs/DB01282ApprovedInvestigationalIt is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Products: Carbetocin Aguettant 100 Mikrogramm/ml Injektionslösung in einer FertigspritzeFimasartan
go.drugbank.com/drugs/DB09279InvestigationalFimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. … It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials.
Categories: Agents Acting on the Renin-Angiotensin SystemDienestrol
go.drugbank.com/drugs/DB00890ApprovedWithdrawnUsing or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of the vulva. … It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy.