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Displaying results 3191 - 3200 of 10000 in total
  1. Drug

    Diloxanide

    go.drugbank.com/drugs/DB08792
    Experimental

    Diloxanide (as [Diloxanide furoate]) is an anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections. … Although it is not currently approved for use in the United States, it was approved by a CDC study in the treatment of 4,371 cases of Entamoeba histolytica from 1977 to 1990.

  2. Drug

    Vevorisertib

    go.drugbank.com/drugs/DB21481
    Investigational

    (MK-4440-001)). … Vevorisertib has a monoisotopic molecular weight of 586.32 Da.

  3. Drug

    Tipapkinogene sovacivec

    go.drugbank.com/drugs/DB06239
    Investigational

  4. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Ocedurenone has a monoisotopic molecular weight of 503.21 Da.

  5. Drug

    Xylose

    go.drugbank.com/drugs/DB09419
    ApprovedWithdrawn

    D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. Xylose has also been used as a diagnostic agent to observe malabsorption.

  6. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0001628
    TargetShigella flexneri

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Synonyms: PRI
  7. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0003268
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Synonyms: PRI
  8. Drug

    Tovorafenib

    go.drugbank.com/drugs/DB15266
    ApprovedInvestigational

    [A263597] It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 InducersSynonyms: 4-Pyrimidinecarboxamide, 6-amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-, 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl)ethyl)-4-pyrimidinecarboxamide
  9. Drug

    IC41

    go.drugbank.com/drugs/DB05776
    Investigational

    It is being devloped by Intercell AG for the treatment of hepatitis C.

  10. Drug

    Phosphoaminophosphonic acid guanylate ester

    go.drugbank.com/drugs/DB02082
    Experimental

    It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.

    Synonyms: 5'-guanylylimidodiphosphate, Guanosine 5'-[beta,gamma-imido]triphosphate