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Maxy-G34
go.drugbank.com/drugs/DB05718InvestigationalMAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). … , while Neulasta has a single 20 Kd PEG group attached at the N terminal end of the wild type G-CSF protein.
Categories: Compounds used in a research, industrial, or household settingMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Synonyms: (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamide, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamidePralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes. … [A246693] Compared to methotrexate, pralatrexate has better accumulation in cancer cells.
Synonyms: N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid, (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acidCystine
go.drugbank.com/drugs/DB00138ApprovedInvestigationalNutraceuticalWithdrawnA covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
Synonyms: L-Cystine, L-DicysteineBismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnThe use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA. … Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic
2,2'-Dibenzothiazyl disulfide
go.drugbank.com/drugs/DB14201Approved2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer. … Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Omacetaxine mepesuccinate
go.drugbank.com/drugs/DB04865ApprovedInvestigationalWithdrawnOmacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies … Then in March 2006, it received Orphan Drug status from the FDA for the treatment of CML.
Synonyms: 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioateTiaprofenic acid
go.drugbank.com/drugs/DB01600ApprovedTiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. … It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Fructose
go.drugbank.com/drugs/DB04173ApprovedInvestigationalCategories: Compounds used in a research, industrial, or household settingAmdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnIt is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.