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Displaying results 3211 - 3220 of 8698 in total
  1. Target

    Methylaspartate ammonia-lyase

    go.drugbank.com/bio_entities/BE0003325
    TargetCitrobacter amalonaticus

    Involved in the methylaspartate cycle. Catalyzes the formation of the alpha,beta-unsaturated bond by the reversible anti elimination of ammonia from L-threo-beta-methylaspartate (L-threo-(2S,3S)-3-methylaspartate) to give mesaconate (By ...

    Synonyms: MAL
  2. Drug

    Novobiocin

    go.drugbank.com/drugs/DB01051
    ApprovedInvestigationalVet approvedWithdrawn

    Novobiocin is an antibiotic compound derived from _Streptomyces niveus_. It has a chemical structure similar to coumarin. … In 2009, the FDA determined novobiocin sodium was withdrawn from sale for reasons of safety or effectiveness.[L44062,L43942]

  3. Drug

    Prednisolone phosphate

    go.drugbank.com/drugs/DB14631
    ApprovedInvestigationalVet approved

    Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.

    Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2A6 Inducers
  4. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    Lazertinib is an oral, third-generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). … [A264299, A264304] Lazertinib was first approved in South Korea on January 18, 2021, for the treatment of _EGFR_ T790M mutation-positive non-small cell lung cancer (NSCLC) with EGFR mutations.

    Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 SubstratesProducts: Clarelux 500 Mikrogramm/g Schaum zur Anwendung auf der Haut
  6. Drug

    Daclatasvir

    go.drugbank.com/drugs/DB09102
    ApprovedInvestigationalWithdrawn

    Combination therapies that include daclatasir can be used for challenging-to-treat patients who have HIV-1 coinfection, advanced cirrhosis, or post-liver transplant recurrence of HCV [L863]. … Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV).

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Levopropoxyphene

    go.drugbank.com/drugs/DB06793
    ApprovedWithdrawn

    It was sold as an antitussive, but it was removed from the market in the 70s.[T133] Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962.

  8. Drug

    Isoprenaline

    go.drugbank.com/drugs/DB01064
    ApprovedInvestigational

    Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion

    Categories: Adrenergics for Systemic Use, Drugs for Obstructive Airway DiseasesProducts: Isoprenalin Macure 0,2 mg/ml Konzentrat zur Herstellung einer Infusionslösung
  9. Drug

    PH-284

    go.drugbank.com/drugs/DB05452
    Experimental

    PH-284 is under investigation by Pherin and Organon for the treatment of anorexia nervosa, and loss of appetite and cachexia in cancer and AIDS patients. … PH-284 belongs to a new family of new chemical entities called vomeropherins.

  10. Drug

    Safflower oil

    go.drugbank.com/drugs/DB09446
    ApprovedInvestigationalWithdrawn

    Safflower oil is approved for use as an indirect additive in food contact substances and is readily available as a food ingredient. … Gamma linolenic acid (GLA) safflower oil is marketed as an over-the-counter dietary supplement.