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Serplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalMost recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953] … Serplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor.
Lercanidipine
go.drugbank.com/drugs/DB00528ApprovedInvestigationalWithdrawnLercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Mixtures: ENALAPRIL E LERCANIDIPINA EG, ENALAPRIL E LERCANIDIPINA EGHydrogenated soybean oil
go.drugbank.com/drugs/DB11302ApprovedExtracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils. … According to the FDA, hydrogenated soybean oil is generally recognized as safe (GRAS) food substance.
Manidipine
go.drugbank.com/drugs/DB09238ApprovedInvestigationalWithdrawnIt is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.
Delafloxacin
go.drugbank.com/drugs/DB11943ApprovedInvestigationalIt was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial skin and skin structure infections. … Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections,
Dalfampridine
go.drugbank.com/drugs/DB06637ApprovedInvestigationalDalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients.
Catridecacog
go.drugbank.com/drugs/DB09310ApprovedIn these patients, activated rFXIII has been shown to increase the mechanical strength of fibrin clots, slow down fibrinolysis, and to enhance platelet adhesion to the site of injury. … As the half-life of endogenous Factor XIII is long (5-11 days), prophylactic therapy with the replacement of FXIII can be given every 4-6 to maintain hemostasis[A32363].
Zidesamtinib
go.drugbank.com/drugs/DB21623ApprovedInvestigationalof resistance mutations, particularly the solvent front G2032R substitution, and progression of disease in the brain. … Zidesamtinib is an orally administered ROS1 kinase inhibitor designed to remain active against ROS1 resistance mutations.
Iobenguane sulfate I-123
go.drugbank.com/drugs/DB09546ApprovedIobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].
Halothane
go.drugbank.com/drugs/DB01159ApprovedVet approvedWithdrawnAnalgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required.