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Interferon alfa-n1
go.drugbank.com/drugs/DB00011ApprovedWithdrawnInterferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated.
SW033291
go.drugbank.com/drugs/DB32765Experimental[A275473, A275474] It has been found to increase prostaglandin E2 (PGE2) and is being investigated in accelerating of hematopoietic recovery and treating type 2 diabetes mellitus.[A275473, A275474]
G4544
go.drugbank.com/drugs/DB05244ExperimentalIt targets bone tissue and is actively incorporated into bone mineral at sites where bone is metabolically active.
Azaperone
go.drugbank.com/drugs/DB11376InvestigationalVet approvedAt the same time, the agent generally does not see equine use as particular adverse reactions may happen. More rarely it may be used in humans as an antipsychotic drug, but this is uncommon. … It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs and elephants.
Products: AZANIL 40MG/ML INJECTIONNP2
go.drugbank.com/drugs/DB06308InvestigationalIt was under investigation in clinical trial NCT01291901 (NP2 Enkephalin For Treatment of Intractable Cancer Pain).
Mechlorethamine
go.drugbank.com/drugs/DB00888ApprovedInvestigationalIt was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. … The FDA granted marketing approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL
Zeaxanthin
go.drugbank.com/drugs/DB11176ApprovedInvestigationalIt gives the distinct yellow color to many vegetables and other plants including paprika, corn, saffron and wolfberries. … It is available as a dietary supplement for eye health benefits and potential prevention of age-related macular degeneration. Zeaxanthin is also added as a food dye.
Crisaborole
go.drugbank.com/drugs/DB05219ApprovedInvestigationalIt is currently under development as topical treatment of psoriasis. … It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a good safety profile.
Betrixaban
go.drugbank.com/drugs/DB12364ApprovedIt was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [A27286]. … VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [A27287].
Odevixibat
go.drugbank.com/drugs/DB16261ApprovedInvestigationalOdevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC). Odevixibat is the first approv...