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Displaying results 3231 - 3240 of 10000 in total
  1. Target

    Cyclin-dependent kinase 9

    go.drugbank.com/bio_entities/BE0002207
    TargetHumans

    This complex is inactive when in the 7SK snRNP complex form (PubMed:10574912, PubMed:10757782, PubMed:11145967, PubMed:11575923, PubMed:11809800, PubMed:11884399, PubMed:14701750, PubMed:16109376, PubMed … The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro (PubMed:21127351).

    Synonyms: Tat-associated kinase complex catalytic subunit
  2. Target

    Proteasome subunit beta type-5

    go.drugbank.com/bio_entities/BE0002348
    TargetHumans

    Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity … Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.

    Synonyms: Multicatalytic endopeptidase complex epsilon chain
  3. Drug

    Metocurine

    go.drugbank.com/drugs/DB01336
    Approved

    Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393]

  4. Drug

    Chlormezanone

    go.drugbank.com/drugs/DB01178
    ApprovedWithdrawn

    A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.

    Synonyms: 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide
  5. Drug

    Tifuvirtide

    go.drugbank.com/drugs/DB05413
    Investigational

    It has received fast-track designation from the FDA and is in Phase I/II clinical testing.

    Categories: Gene Products, env, env Gene Products, Human Immunodeficiency Virus
  6. Drug

    Depreotide

    go.drugbank.com/drugs/DB11628
    ApprovedWithdrawn

    Depreotide is an ingredient in the EMA-withdrawn product NeoSpect.

  7. Drug

    Hesperidin

    go.drugbank.com/drugs/DB04703
    ApprovedInvestigational

    Hesperidin is a flavan-on glycoside found in citrus fruits.

  8. Drug

    1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))

    go.drugbank.com/drugs/DB11331
    ApprovedWithdrawn

    Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label].

    Salts: 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium saltSynonyms: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol
  9. Drug

    GI-4000

    go.drugbank.com/drugs/DB05698
    Investigational

    A vaccine containing a heat-killed recombinant <em>Saccharomyces cerevisiae</em> yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant

  10. Drug

    Nafamostat

    go.drugbank.com/drugs/DB12598
    Investigational

    The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing continuous renal replacement therapy due to acute kidney injury. … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome.