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Remdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigationalSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia … [A191427, A198810] Remdesivir was confirmed as a non-obligate chain terminator of RdRp from SARS-CoV-2 and the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical
Categories: MATE 1 Inhibitors, Approved Treatments for COVID-19Products: VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET, VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIALSodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigational[L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and a metabolite of the inhibitory neurotransmitter GABA. … [A18723] For safety reasons, sodium oxybate is a controlled substance only available through a restricted program in approved countries.
Products: Natriumoxybat Kalceks 500 mg/ml Lösung zum Einnehmen, Natriumoxybat neuraxpharm 500 mg/ml Lösung zum EinnehmenMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
International brands: Almagel T, Almadrat TMixtures: M A L D I M, ASIDOPAN PLUS 200 ML SUSPANSIYONAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalThis recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: ILT-101, 125-L-Serine-2-133-interleukin 2Obinutuzumab
go.drugbank.com/drugs/DB08935ApprovedInvestigational[L54521] It was developed as a Type II anti-CD20 antibody to improve upon first-generation agents like rituximab. … Obinutuzumab is a humanized anti-CD20 monoclonal antibody designed to treat B-cell malignancies.
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: GAZYVA 1000 MG IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 MLTezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigationalBlocking the interaction of TSLP with the receptors TSLPR and IL-7Rα improves asthma-associated biomarkers including eosinophil counts and IgE, FeNO, IL-5, and IL-13 levels. … It was granted FDA approval on December 17, 2021, and is currently marketed under the trademark TEZSPIRE by Amgen/AstraZeneca.
Synonyms: AMG 157, AMG-157Products: Tezspire 210 mg/1,91 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), TEZSPIRE®Nilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalNilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). … ), another tyrosine kinase inhibitor used as a first-line treatment for CML.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TASIGNA® 150 MG CAPSULAS, TASIGNA 150 MG KAPSUL, 28 ADETGroup 10 secretory phospholipase A2
go.drugbank.com/bio_entities/BE0000070TargetEnzymeHumansSecretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:12021277, PubMed:9188469). Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preferen...
Polypeptides: Group 10 secretory phospholipase A2Synonyms: Phosphatidylcholine 2-acylhydrolase 10Interleukin-10 receptor subunit alpha
go.drugbank.com/bio_entities/BE0014391TargetHumansCell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, all...
Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1Bcl-2-like protein 10
go.drugbank.com/bio_entities/BE0019838TargetHumansPromotes cell survival by suppressing apoptosis induced by BAX but not BAK (PubMed:11278245, PubMed:11689480). Increases binding of AHCYL1/IRBIT to ITPR1 (PubMed:27995898). Reduces ITPR1-mediated calcium release from the endoplasmic reti...
Polypeptides: Bcl-2-like protein 10Synonyms: Bcl2-L-10