Search
Potassium perchlorate
go.drugbank.com/drugs/DB09418ApprovedWithdrawnPotassium is most commonly used in flares and automobile airbags [A32609]. … Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates.
Categories: Sex Hormones and InsulinsProducts: Perchloracap Capsule 200mgBenzhydrocodone
go.drugbank.com/drugs/DB15465ApprovedIt was first approved by the FDA in February 2018 in combination with [acetaminophen] under the trade name Apadaz, marketed by KVK Tech and developed by KemPharm.[L7859,L7862] … Benzhydrocodone is a benzylic prodrug of hydrocodone.[L4894] It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse.
Mixtures: Benzhydrocodone and Acetaminophen, Benzhydrocodone and AcetaminophenTranscription factor p65
go.drugbank.com/bio_entities/BE0005551TargetHumansThe dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity … NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Serine/threonine-protein kinase Nek1
go.drugbank.com/bio_entities/BE0009496TargetHumansPhosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:20230784). … Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:20230784).
Synonyms: Never in mitosis A-related kinase 1Plicamycin
go.drugbank.com/drugs/DB06810ApprovedWithdrawnPlicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. … It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Categories: Compounds used in a research, industrial, or household setting, Indicators and ReagentsRopeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients. … Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for
Categories: Amino Acids, Peptides, and Proteins, Interferon Type ISynonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bMirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigational[L46252] It was officially approved in the EU in May 2023[L48656] and Canada in July 2023[L48661], and was eventually approved in the US in October 2023[L48651] for the treatment of adult patients with … Mirikizumab is a monoclonal antibody developed by Eli Lilly intended to treat ulcerative colitis.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsG17DT Immunogen
go.drugbank.com/drugs/DB04914InvestigationalIt is also in a phase II/III trial for advanced stomach cancer in combination with 5-fluorouracil and cisplatin and in a late phase II trial for advanced colorectal cancer in combination with irinotecan … It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine.
Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone AntagonistsSynonyms: G17DT (AN ANTIGASTRIN IMMUNOGEN)Tegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalWhen converted and bioactivated to 5-FU, the drug mediates an anticancer activity by inhibiting thymidylate synthase (TS) during the pyrimidine pathway involved in DNA synthesis. 5-FU is listed on the … It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with [DB09257] and [DB03209], or along with [DB00544] as [DB09327].
Categories: Fluorouracil and prodrugs, Antineoplastic and Immunomodulating AgentsInternational brands: ESUEEW AN TGepotidacin
go.drugbank.com/drugs/DB12134ApprovedInvestigational[L52680] In March 2025, gepotidacin was approved by the FDA for the treatment of uncomplicated urinary tract infections in select patients. … Gepotidacin is a first-in-class triazaacenaphthylene antibacterial targeting bacterial DNA gyrase and topoisomerase IV.[L52685] Its target is similar to that of fluoroquinolone antibacterials - e.g.
Categories: Triazaacenaphthylene Bacterial Type II Topoisomerase Inhibitor