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Methoxy polyethylene glycol-epoetin beta
go.drugbank.com/drugs/DB09107ApprovedInvestigationalESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
PPI-1019
go.drugbank.com/drugs/DB05832InvestigationalApan (PPI-1019) is developed by Praecis Pharmaceuticals to treat Alzheimer's Disease.
rsPSMA Vaccine
go.drugbank.com/drugs/DB06361ApprovedWithdrawnan ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on
Gallium chloride Ga-67
go.drugbank.com/drugs/DB14550ApprovedGallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with [sodium citrate] to generate [gallium citrate Ga 67], which can be used to image certain cancers
Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigational[A251405] Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and to assist in specific surgical procedures such as cystourethroscopy. … [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to aid in visualizing ureter integrity in cystoscopic assessments.[L42600]
RPI-78M
go.drugbank.com/drugs/DB05740ExperimentalOther neurological disorders that may be served by RPI-78M include myasthenia gravis (MG), muscular dystrophy (MD) and amyotrophic lateral sclerosis (ALS).
Zimelidine
go.drugbank.com/drugs/DB04832ApprovedWithdrawnZimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving … Additionally, zimelidine was charged to cause an increase in suicidal ideation and/or attempts among depressive patients.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTaspoglutide
go.drugbank.com/drugs/DB14027InvestigationalIn September 2010 Roche halted Phase III clinical trials due to incidences of serious hypersensitivity reactions and gastrointestinal side effects. As of May 2013 no new trials had been registered. … Taspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche.
Larazotide
go.drugbank.com/drugs/DB05645InvestigationalAn octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.
Dexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawnIt appears to inhibit formation of a toxic iron-anthracycline complex.
International brands: Ao Nuo Xian