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Nepicastat
go.drugbank.com/drugs/DB12979InvestigationalNepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Synonyms: (S)-5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingLFF-571
go.drugbank.com/drugs/DB13013InvestigationalLFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection.
Categories: Heterocyclic Compounds, 1-RingDasolampanel etibutil
go.drugbank.com/drugs/DB12049InvestigationalDasolampanel etibutil has been used in trials studying the treatment of Diabetic Neuropathy, Painful.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRislenemdaz
go.drugbank.com/drugs/DB12063InvestigationalMk 0657 has been used in trials studying the treatment of Major Depressive Disorder.
Categories: Receptors, N-Methyl-D-Aspartate, antagonists & inhibitors, Heterocyclic Compounds, 1-RingAvoralstat
go.drugbank.com/drugs/DB12120InvestigationalAvoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Synonyms: 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine-2-carboxylic acid, 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine-2-carboxylic acidCategories: Heterocyclic Compounds, 1-RingBalicatib
go.drugbank.com/drugs/DB12239InvestigationalBalicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.
Categories: Heterocyclic Compounds, 1-RingCarmegliptin
go.drugbank.com/drugs/DB12268InvestigationalCarmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2.
Categories: Dipeptidyl Peptidase 4, Heterocyclic Compounds, 2-RingMuscimol
go.drugbank.com/drugs/DB12458InvestigationalMuscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
Synonyms: 5-(aminomethyl)-3(2H)-isoxazoloneCategories: GABA-A Receptor Agonists, Heterocyclic Compounds, 1-RingLetrazuril
go.drugbank.com/drugs/DB12663InvestigationalLetrazuril has been used in trials studying the treatment of HIV Infections and Cryptosporidiosis.
Categories: Heterocyclic Compounds, 1-RingZunsemetinib
go.drugbank.com/drugs/DB16502InvestigationalZunsemetinib is being investigated in a new clinical trial (NCT06374459) for the treatment of hormone receptor-positive and HER2-negative metastatic breast cancer with bone metastasis. … Additionally, ATI-450 was studied in a terminated trial (NCT05511519) to treat patients with psoriatic arthritis.
Synonyms: (2′S)-3-Chloro-4-[(3,5-difluoro-2-pyridinyl)methoxy]-2′-[2-(1-hydroxy-1-methylethyl)-4-pyrimidinyl]-5′,6-dimethyl[1(2H),4′-bipyridin]-2-one, (P)-3-chloro-4-((3,5-difluoropyridin-2-yl)methoxy)-2'-(2-(2-hydroxypropan-2-yl)pyrimidin-4yl)-5',6-dimethyl-2H-[1,4'-bipyridin]-2-one