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Zidebactam
go.drugbank.com/drugs/DB13090ApprovedZidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2. … [L63350] It is available only in fixed combination with [cefepime], which binds PBP3 and PBP1a/b.
Categories: Heterocyclic Compounds, 1-RingPlecanatide
go.drugbank.com/drugs/DB13170ApprovedInvestigationalPlecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC).
Categories: Guanylate Cyclase-C Agonist, Guanylyl Cyclase C AgonistsGluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalCommonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Synonyms: D-Gluconic AcidMixtures: Normosol-R & 5% Dextrose, Isolyte S With 5% Dextrose InjSodium chlorite
go.drugbank.com/drugs/DB13210InvestigationalFood and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].
Products: Qve - S, V Doctor pure chlorine dioxideTuaminoheptane
go.drugbank.com/drugs/DB13238ExperimentalTuaminoheptane is a sympathomimetic drug typically used as a nasal decongestant.[A198534,A275018]
Synonyms: 2-Heptanamine, 2-AminoheptanePrifinium
go.drugbank.com/drugs/DB13254ExperimentalPrifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome .
Categories: Heterocyclic Compounds, 1-RingAceclidine
go.drugbank.com/drugs/DB13262ApprovedAceclidine is a cholinergic muscarinic agonist which began marketing in Europe in the 1970s for the treatment of glaucoma. … [A274273] It has also been studied in the treatment of presbyopia, a common age-related vision loss where the crystalline lens hardens and loses elasticity, impairing near vision.
Synonyms: 3-AcetoxyquinuclidineDibekacin
go.drugbank.com/drugs/DB13270ApprovedDibekacin is an aminoglycoside antibiotic marketed in Japan .
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexBenzododecinium
go.drugbank.com/drugs/DB13282InvestigationalIt has been marketed as a tincture for antiseptic product for wounds in the Czech Republic.
Categories: Compounds used in a research, industrial, or household setting