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Xylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is avail...
Products: DAH NASENSPRAY 0.1 %, IMIDIN N NASENSPRAYCyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalCyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis a...
Mixtures: Vita Day Tab, One A Day TabProducts: Rubramin PC, VITAMIN B12 RATIOPHARM NAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigationalAcyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and so...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: AVIREX-U, ACIC 250 PI VIAFish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalFish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient,...
Mixtures: SmofKabiven N-Plus zentral Emulsion zur Infusion, SmofKabiven N-Plus zentral elektrolytfrei Emulsion zur InfusionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHeparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalUnfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da.
Mixtures: BARICUS 50 IU/%1/%10 JEL , 50 G, HEPARINISED SALINE INJECTION 10 iu/mlProducts: Hep-Lock U/P, HEPARIN NA BRA 25000IEDiacylglycerol kinase delta
go.drugbank.com/bio_entities/BE0002297TargetHumansDiacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:12200442, PubMed:23949095).
Synonyms: DAG kinase deltaFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigational[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation
Categories: P-glycoprotein substratesProducts: Dg Health Aller Ease, FEXODINA® NF 30 MG / 5 ML SUSPENSIÓN ORALBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigationalBudesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. Budesonide was granted FDA approval o...
Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPhylloquinone
go.drugbank.com/drugs/DB01022ApprovedInvestigationalVitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin. Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X. It is indicated ...
Mixtures: Vitalipid N, Vitalipid NCategories: Warfarin Reversal AgentHuman immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIntravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and io...
Synonyms: Human gamma globulinProducts: Gamimune N 5% (iv), Gamimune N 10% (iv)