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Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]
Products: PMS-glyburideSucralfate
go.drugbank.com/drugs/DB00364ApprovedInvestigationalIt was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076]. … Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms.
Products: PMS-sucralfateFingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigationalIt was developed by Novartis and initially approved by the FDA in 2010.[L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 virus.
Products: PMS-fingolimodPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigational[A176810] Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as key regulators of cell growth. … [L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male
Products: PMS-palbociclibOlanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigational[A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] … [A176996] Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring.
Products: Olanzapine Glenmark Europe, PMS-olanzapinePravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigational[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. … [T274] This drug was developed by Sankyo Co. Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991.
Mixtures: Pravigard Pac, Pravigard PacProducts: PMS-pravastatinIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204134] When compared to [hydrochlorothiazide] (another commonly prescribed diuretic), indapamide has been shown to be superior at lowering systolic blood pressure, reducing left ventricular mass index … [A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription
Mixtures: PMS-perindopril-indapamide, PMS-perindopril-indapamideProducts: PMS-indapamidePlatelet glycoprotein 4
go.drugbank.com/bio_entities/BE0010538TargetTransporterHumansMultifunctional glycoprotein that acts as a receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-densit...
Synonyms: PAS-4, PAS IVCyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigationalCyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in ...
Products: PMS-cyproheptadine HCl Tab 4mg, Euro-cyproheptadine 2mg/5mlVincristine
go.drugbank.com/drugs/DB00541ApprovedInvestigationalIt is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. … Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy
Products: Vincasar PFS