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Phenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approvedPhenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A6 Substrates with a Narrow Therapeutic IndexProducts: Epilan-D 100 mg - Tabletten, Epilan-D 50 mg/ml - AmpullenVancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalIt is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and enterocolitis
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Vancomycin Dr. Eberth 125 mg Hartkapseln, Vancomycin Dr. Eberth 250 mg HartkapselnIbandronate
go.drugbank.com/drugs/DB00710ApprovedInvestigational[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.[A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805] … Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].
Mixtures: IBONE D®, IBONE D 30000Products: ASCENDRA 3MG DUO D3 1 + 90, BONDRONAT® CONCENTRADO DE SOLUCION PARA INFUSION 6 MG/6ML.Folic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedFolic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … DNA synthesis in rapidly dividing cells, and therefore prevent the formation of DHF and THF.
Mixtures: One A Day Tab, Extra Once A DayProducts: Folic D3, ACIDO FOLICO DOC GENERICIAscorbic acid
go.drugbank.com/drugs/DB00126ApprovedInvestigationalNutraceuticalA six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. … Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Mixtures: One A Day Tab, Extra Once A DayCategories: Compounds used in a research, industrial, or household settingBevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigational[A193272,A193275,L12648] Avastin was subsequently approved by Health Canada on March 24, 2010 and by the European Commission on April 21, 2021. … [A192834,A192888,A192837,A192891,A192894] Bevacizumab is a humanized monoclonal IgG antibody that inhibits angiogenesis by binding and neutralizing VEGF-A.
Synonyms: Bei Fa Zhu DankangProducts: KRABEVA Bevacizumab (r-DNA Origin) Concentrate for Solution for Intravenous Infusion 25mg/mLOlopatadine
go.drugbank.com/drugs/DB00768ApprovedAn ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. … It is a structural analog of [doxepin], which has a minimal anti-allergic activity.
Products: OLO-A-DAY, Pataday Twice A Day ReliefImipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine may be used to treat depression and nocturnal enuresis in children [FDA Label]. … Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexInternational brands: Imipramin DakNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of it...
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: DG Health nicotine, Dg Health NicotineDimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigational[A253917] Prior to its FDA approval, dimethyl fumarate had been used in Germany for treatment of psoriasis.[A253917] … [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide
Products: D-FUMARIC 240 CAPSULAS DE LIBERACIÓN RETARDADA 240 MG, D-FUMARIC 120 CAPSULAS DE LIBERACION RETARDADA 120 MG