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Tolazoline
go.drugbank.com/drugs/DB00797ApprovedVet approvedWithdrawnTolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. … It is used in treatment of persistent pulmonary hypertension of the newborn.
Categories: Adrenergic alpha-1 Receptor AntagonistsFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICACategories: Corticosteroid Hormone Receptor AgonistsCarprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnIt was generally well tolerated, with the majority of adverse effects being mild, such as gastro-intestinal pain and nausea, similar to those recorded with aspirin and other non-steroidal anti-inflammatory … Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs.
Cyclandelate
go.drugbank.com/drugs/DB04838ApprovedWithdrawnCyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries. … A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia.
Ethylenediamine
go.drugbank.com/drugs/DB14189ApprovedSensitivity to ethylenediamine may be identified with a clinical patch test. … Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Forasartan
go.drugbank.com/drugs/DB01342ExperimentalForasartan competes with angiotensin II for binding at the AT1 receptor subtype. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.
Categories: Agents Acting on the Renin-Angiotensin System, Angiotensin Receptor AntagonistsAvacopan
go.drugbank.com/drugs/DB15011ApprovedInvestigationalfragment C5a and its cognate C5aR receptor in AAV. … presence of ANCAs in the serum.
Categories: Complement 5a Receptor AntagonistEugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalIts exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction. … There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache.
Amisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigationalIn the US, the intravenous formulation of amisulpride is used to treat and prevent postoperative nausea and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of … [L32759] It is marketed under the brand name Barhemsys.
Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor AntagonistsRipasudil
go.drugbank.com/drugs/DB13165InvestigationalThis medication is available in the form of a 0.4% eye drop solution under the brand name Glanatec. … Ripasudil is a well tolerated medication that is used when other drugs have been proven to be non-effective or cannot be administered.