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Nalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalA narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Synonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriolAnemia, Pernicious
go.drugbank.com/conditions/DBCOND0004065Drugs: Ammonium molybdate · Cyanocobalamin · Ferrous cysteine glycinate · Hydroxocobalamin · Pyridoxal phosphateSynonyms: PA - Pernicious anaemiaMKC1106-PP
go.drugbank.com/drugs/DB06030ExperimentalMKC1106-PP was under investigation in clinical trial NCT00423254 (Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.). … MKC1106-PP is a 3-component investigational vaccine made up of a DNA plasmid (pPRA-PSM) and 2 peptides E-PRA and E-PSM.
Transcrocetinate
go.drugbank.com/drugs/DB05974InvestigationalVitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Categories: Compounds used in a research, industrial, or household settingAstraZeneca COVID-19 Vaccine
go.drugbank.com/drugs/DB15656ApprovedInvestigationalclots in association with thrombocytopenia - a causal link with the vaccine has not been proven, but is possible and requires further analysis. … [L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another human coronavirus, Middle Eastern respiratory
Levocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalIt is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Synonyms: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner saltTenocyclidine
go.drugbank.com/drugs/DB01520IllicitInvestigationalIt is more potent than phencyclidine and hence, this drug was classified under the schedule 1 in 1970.
Categories: Compounds used in a research, industrial, or household settingXimelagatran
go.drugbank.com/drugs/DB04898ApprovedWithdrawnIn 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries … Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former.
Synonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetateProcarbazine
go.drugbank.com/drugs/DB01168ApprovedInvestigationalAn antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Synonyms: N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine, N-Isopropyl-α-(2-methylhydrazino)-p-toluamideEladocagene exuparvovec
go.drugbank.com/drugs/DB16780ApprovedInvestigational[A253687] It was subsequently approved by the FDA in November 2024.[L51898,L51893] … [L43642] Eladocagene exuparvovec received EMA approval in July 2022.