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Cytochrome b-c1 complex subunit 10
go.drugbank.com/bio_entities/BE0003859TargetHumansComponent of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit...
Polypeptides: Cytochrome b-c1 complex subunit 10Synonyms: Complex III subunit 10Flavoxate
go.drugbank.com/drugs/DB01148ApprovedA drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. … It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Synonyms: 2-(1-piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate, 2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylateCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSodium glycerophosphate
go.drugbank.com/drugs/DB09561ApprovedGlycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Mixtures: AMINOMIX 1 NOVUM 1500 ML, NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 MLCategories: Blood and Blood Forming Organs, Blood Substitutes and Perfusion SolutionsDaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal … [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name CUBICIN® by Cubist Pharmaceuticals LLC (Merck & Co.).[L32534]
Categories: P-glycoprotein substrates, Amino Acids, Peptides, and ProteinsProducts: XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, XAPTO 500 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADETBenmelstobart
go.drugbank.com/drugs/DB17473InvestigationalAPL 502 is a humanised immunoglobulin G1 (IgG1) monoclonal antibody targeting the programmed cell death-1 ligand-1 (PD-L1).
Synonyms: gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV2-5*01 (78.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116)-Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, , G1v66 CH2 A27 (CH1 K120(213) (117-214), hinge 1-1510 kDa heat shock protein, mitochondrial
go.drugbank.com/bio_entities/BE0009028TargetHumansCo-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of...
Polypeptides: 10 kDa heat shock protein, mitochondrialSynonyms: Chaperonin 10, 10 kDa chaperoninTaste receptor type 2 member 10
go.drugbank.com/bio_entities/BE0020463TargetHumansGustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
Polypeptides: Taste receptor type 2 member 10Thalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnIt has been reintroduced and used for a number of inflammatory disorders and cancers. … Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action.
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsSynonyms: α-N-phthalylglutaramide, (+-)-N-(2,6-dioxo-3-Piperidyl)phthalimidePitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.
Categories: pitavastatin and ezetimibe, Cytochrome P-450 SubstratesProducts: Trolise 1 mg Filmtabletten, PITAMIN 1 MG EFERVESAN TABLET, 30 ADETConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalsulfate, 3% of equilenin sulfate, 5% of 17-alpha and 17-beta-dihydroequilenin sulfate, 2% of 17-alpha-estradiolsulfate and 3% of 17-beta-estradiolsulfate. … [L5605, T475] The conjugated estrogen product contains a mix of estrogen from which about 50% is represented by estrone sulfate followed by 25% of equilin sulfate, 15% of 17-alpha-dehydroequilenin
Mixtures: DUAVİVE 0.45 MG/20 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 TABLET, DUAVIVE 20 mg/0.45 mg modified - release tabletsCategories: Genito Urinary System and Sex Hormones, conjugated estrogens and bazedoxifene