Search

Displaying results 3331 - 3340 of 3481 in total
  1. Drug

    Acoramidis

    go.drugbank.com/drugs/DB17999
    ApprovedInvestigational

    Acoramidis is a small molecule stabilizer of transthyretin (TTR) for use in patients with TTR amyloidosis. Similar to the previously developed tafamidis, acoramidis is used to stabilize TTR in its tetrameric form, preventing the formatio...

    Synonyms: 3-(3-(3,5-dimethyl-1h-pyrazol-4-yl)propoxy)-4-fluorobenzoic acidCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  2. Drug

    Quinoline

    go.drugbank.com/drugs/DB18050
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
  3. Drug

    Opelconazole

    go.drugbank.com/drugs/DB18251
    Investigational

    Synonyms: D-threo-pentitol, 2,5-anhydro-1,3,4-trideoxy-2-c-(2,4-difluorophenyl)-4-((4-(4-(4-(((4-fluorophenyl)amino)carbonyl)phenyl)-1-piperazinyl)-2-methylphenoxy)methyl)-1-(1h-1,2,4-triazol-1-yl)-Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A Inducers
  4. Drug

    Phelimin

    go.drugbank.com/drugs/DB18332
    Experimental

    Phelemin (PHE-MIP) is a methacrylic acid-based copolymer purified to bind to L-phenylalanine and L-phenylalanine-containing peptides.

  5. Drug

    CC-90001

    go.drugbank.com/drugs/DB18445
    Investigational

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  6. Drug

    Revumenib

    go.drugbank.com/drugs/DB18515
    ApprovedInvestigational

    Abnormal gene rearrangements at chromosome locus 11q23, called KMT2A rearrangements or translocations, are present in 5%-10% of patients with acute leukemias and are the sole genetic aberration found in the majority of infant acute lymph...

    Synonyms: Benzamide, n-ethyl-2-((4-(7-((trans-4-((ethylsulfonyl)amino)cyclohexyl)methyl)-2,7-diazaspiro(3.5)non-2-yl)-5-pyrimidinyl)oxy)-5-fluoro-n-(1-methylethyl)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  7. Drug

    SIG-205

    go.drugbank.com/drugs/DB18548
    Experimental

    SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer

  8. Drug

    APPD

    go.drugbank.com/drugs/DB18603
    Experimental

    Synonyms: -L-TALO-HEPTOFURANURONAMIDE, 5-O-(5-AMINO-5-DEOXY-.BETA.Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  9. Drug

    P-42 peptide

    go.drugbank.com/drugs/DB18610
    Experimental

    P-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein

  10. Drug

    IDUA-RTB

    go.drugbank.com/drugs/DB18612
    Experimental

    RTB-IDUA is a fusion protein of alpha-L-iduronidase (IDUA) and ricin transport subunit B (RTB).