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Displaying results 3331 - 3340 of 10000 in total
  1. Drug

    Gemifloxacin

    go.drugbank.com/drugs/DB01155
    ApprovedInvestigational

    Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. … It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.

  2. Drug

    Sepiapterin

    go.drugbank.com/drugs/DB16326
    ApprovedInvestigational

    enzymes and increasing intracellular concentrations of BH4. … It is a natural precursor of the enzymatic co-factor tetrahydrobiopterin (BH4), which activates PAH and helps reduce blood phenylalanine levels by enhancing the conformational stability of misfolded PAH

  3. Drug

    Trioxsalen

    go.drugbank.com/drugs/DB04571
    ApprovedWithdrawn

    It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. … Like other psoralens it causes photosensitization of the skin.

  4. Drug

    Roxatidine acetate

    go.drugbank.com/drugs/DB08806
    Investigational

    It is currently approved in South Africa under the tradename Roxit.

  5. Drug

    Dicoumarol

    go.drugbank.com/drugs/DB00266
    Approved

    In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases. … Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K.

    Synonyms: di-(4-hydroxy-3-coumarinyl)methane, 3,3'-methylenebis(4-hydroxy-2H-1-benzopyran-2-one)
  6. Drug

    Secobarbital

    go.drugbank.com/drugs/DB00418
    ApprovedVet approved

    It is commonly known as quinalbarbitone in the United Kingdom.

    Categories: combinations of barbiturates
  7. Drug

    Vimseltinib

    go.drugbank.com/drugs/DB17520
    ApprovedInvestigational

    in a lower risk of off-target effects, including hepatotoxicity. … [L52230,A265035] Vimseltinib - under the brand name Romvimza - was approved by the FDA in February 2025 for the treatment of tenosynovial giant cell tumours for which surgical resection is not appropriate

    Synonyms: 2-(isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)pyrimidin-4(3h)-one
  8. Drug

    Testosterone propionate

    go.drugbank.com/drugs/DB01420
    ApprovedInvestigationalVet approvedWithdrawn

    [T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974. … It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone.

    Products: Malogen In Oil Liq 100mg/ml
  9. Drug

    Fenretinide

    go.drugbank.com/drugs/DB05076
    Investigational

    A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-(4-hydroxyphenyl)all-trans retinamide
  10. Drug

    Lefamulin

    go.drugbank.com/drugs/DB12825
    Approved

    [A183161] The chemical structure of lefamulin contains a tricyclic mutilin core that is necessary for some of its antimicrobial activity.[A183167] … Lefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia.