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Metallo-beta-lactamase type 2
go.drugbank.com/bio_entities/BE0001212TargetEnzymeBacteroides fragilisConfers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
Synonyms: Carbapenem and cephamycin resistanceParaldehyde
go.drugbank.com/drugs/DB09117ApprovedWithdrawnParaldehyde is used as an ingredient in some cough medicines as an expectorant, but its efficacy for this indication has not been confirmed and its use as an expectorant may possibly be due to a placebo … It is classified as a central nervous system (CNS) depressant and has also been found to be an effective anticonvulsant, hypnotic and sedative agent due to its CNS depressant properties.
Categories: Hypnotics and SedativesDofetilide
go.drugbank.com/drugs/DB00204ApprovedInvestigationaland flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. … Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation
Obstructive Sleep Apnea (OSA)
go.drugbank.com/conditions/DBCOND0040865Drugs: ModafinilSynonyms: Obstructive Sleep Apnea Syndrome andHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedIt may also be used to prevent nausea, vomiting, and motion sickness.
Mixtures: Hydrocodone Bitartrate and Homatropine Methylbromide, Hydrocodone Bitartrate and Homatropine MethylbromideCategories: Alimentary Tract and Metabolism, Belladonna and Derivatives, PlainSodium phosphate, monobasic, unspecified form
go.drugbank.com/drugs/DB14503ApprovedMixtures: Up and Up Ready To Use Enema, Pure and Gentle LaxativeSynonyms: Sodium phosphate, monobasic, unspecified formTeclistamab
go.drugbank.com/drugs/DB16655ApprovedInvestigational[A253587] Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug to recruit CD3-expressing T cells to BCMA-expressing … [L43612] Teclistamab was later granted accelerated approval by the FDA on October 25, 2022.[L43617]
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsFavipiravir
go.drugbank.com/drugs/DB12466ApprovedInvestigational[A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for … [A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.
Human Umbilical Cord Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15726InvestigationalStem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. … UC mesenchymal cells derived from Wharton’s jelly are the most studied and offer more stable and better osteogenic and adipogenic differentiation potentials.
Synonyms: UC MSCs, UC-MSCsHuman papillomavirus type 16 L1 capsid protein antigen
go.drugbank.com/drugs/DB10301ApprovedInvestigationalThe vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant *Saccharomyces … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) types 6, 11, 16 and 18.
Categories: Amino Acids, Peptides, and Proteins