Search
Pibrentasvir
go.drugbank.com/drugs/DB13878ApprovedInvestigationalPibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. … The ultimate goal of the combination treatment is to achieve sustained virologic response (SVR) and cure the patients from the infection.
Mixtures: MAVIRET® 100/40 MG TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, P-glycoprotein substratesCladosporium cladosporioides
go.drugbank.com/drugs/DB10431ApprovedCladosporium cladosporioides is a fungus which can provoke allergic reactions. Cladosporium cladosporioides extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureSodium tartrate
go.drugbank.com/drugs/DB13707ApprovedWithdrawnThis compound is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed 4% concentration, according to Health Canada regulations [L2594]. … Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing.
Synonyms: sodium L-tartrate, Disodium L-(+)-tartrateAntipyrine
go.drugbank.com/drugs/DB01435ApprovedAn analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Mixtures: CALZAS®, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesPramlintide
go.drugbank.com/drugs/DB01278ApprovedInvestigationalIt is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes. … Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals.
Lisocabtagene maraleucel
go.drugbank.com/drugs/DB16582ApprovedInvestigational[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. … Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene autoleucel] and [axicabtagene ciloleucel].
Categories: CD19-Directed Genetically Modified Autologous T-cell ImmunotherapiesFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter. … [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideNicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalIt has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. … It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Cardene SR, CARDIBLOC-SR CAPSULE 40 mgDeferoxamine
go.drugbank.com/drugs/DB00746ApprovedInvestigationalIt forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Deferrioxamine BAminolevulinic acid
go.drugbank.com/drugs/DB00855ApprovedInvestigationalA compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Synonyms: 5-ALA, δ-ALAProducts: Alacare 8 mg wirkstoffhaltiges Pflaster