Search

Displaying results 3351 - 3360 of 10000 in total
  1. Drug

    Fotemustine

    go.drugbank.com/drugs/DB04106
    Investigational

    Categories: Antineoplastic and Immunomodulating AgentsSynonyms: (+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate, Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate
  2. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedInvestigationalWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    Synonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-olCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  3. Drug

    Dabrafenib

    go.drugbank.com/drugs/DB08912
    ApprovedInvestigational

    Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway.

    Categories: Heterocyclic Compounds, 1-Ring, Organic Anion Transporter 1 InhibitorsProducts: TAFINLAR (CAPSULES 50 MG), TAFINLAR 50 MG KAPSUL, 20 ADET
  4. Drug

    Perazine

    go.drugbank.com/drugs/DB12710
    ApprovedWithdrawn

    Perazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.

    Categories: Heterocyclic Compounds, 3-RingProducts: PERAZIN-NEURAX 100 MG, PERAZIN-NEURAX 25 MG
  5. Drug

    Nevirapine

    go.drugbank.com/drugs/DB00238
    ApprovedInvestigational

    A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS.

    Mixtures: LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg), TRIVIRO LNS® LAMIVUDINA 150 MG NEVIRAPINA 200 MG ESTAVUDINA 40 MGCategories: Heterocyclic Compounds, 1-Ring, Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
  6. Drug

    Xylitol

    go.drugbank.com/drugs/DB11195
    ApprovedInvestigational

    The recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … It is widely used as a sugar substitute and in "sugar-free" food products.

    Mixtures: Fluor-a-day, Fluor-a-dayCategories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household setting
  7. Drug

    Simeprevir

    go.drugbank.com/drugs/DB06290
    ApprovedWithdrawn

    or longer to 12 or 24 weeks [A19630] depending on prior response status and presence of HIV-1 co-infection. … The SVR12 was 83% (29/35) in treatment-naïve patients and 86% (19/22) in relapsing patients.

    Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and AntisepticsProducts: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADET
  8. Drug

    Drospirenone

    go.drugbank.com/drugs/DB01395
    ApprovedInvestigational

    Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic events. … Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol].

    Synonyms: 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactoneMixtures: Angeliq 1 mg/2 mg Filmtabletten, ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET
  9. Target

    Deoxycytidylate 5-hydroxymethyltransferase

    go.drugbank.com/bio_entities/BE0003183
    TargetEnterobacteria phage T4

    Polypeptides: Deoxycytidylate 5-hydroxymethyltransferaseFunction: deoxycytidylate 5-hydroxymethyltransferase activity
  10. Target

    Histone deacetylase 5

    go.drugbank.com/bio_entities/BE0009578
    TargetHumans

    In vitro, it deacetylates lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:10220385). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional reg...

    Polypeptides: Histone deacetylase 5