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Human Interleukin 8
go.drugbank.com/drugs/DB16456InvestigationalInterleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).
Asimadoline
go.drugbank.com/drugs/DB05104InvestigationalAsimadoline is an orally administered agent that acts as a kappa opioid receptor agonist.
AC-100
go.drugbank.com/drugs/DB05671InvestigationalAC-100 is a novel synthetic peptide derived from an endogenous human protein produced by bone and dental cells (a fragment from matrix extracellular phosphoglycoprotein).
Cipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigational[A232955, A232960] In September 2023, the FDA also approved cipaglucosidase alfa for similar indications.[L49241]
LetibotulinumtoxinA
go.drugbank.com/drugs/DB16820Approved[A249920] It was subsequently approved by the FDA in 1992 for use in aesthetic procedures and has since become one of the most popular cosmetic procedures worldwide.
Synonyms: BoNT/A-DSCefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigationalThe activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus_ is due to its high stability toward beta-lactamases. … [A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence of multidrug-resistant bacteria might be some of the factors leading to an increase in the
CTx-PDE6b
go.drugbank.com/drugs/DB17858InvestigationalBeing commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to _PDE6b_ gene mutations.[L46757] … CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human _PDE6b_ gene.
GSK-1521498
go.drugbank.com/drugs/DB12886InvestigationalGSK1521498 has been used in trials studying the treatment of Obesity and Alcoholism.
Categories: Receptors, Opioid, muEthinamate
go.drugbank.com/drugs/DB01031ApprovedIllicitWithdrawnLike many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient.
Fluoride ion F-18
go.drugbank.com/drugs/DB09398ApprovedInvestigationalIncreased deposition around joints can occur in arthritis and following trauma and increased deposition in bone has been noted around fracture sites, in osteomyelitis, fibrous dysplasia, spondylitis tuberculosa