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Displaying results 3381 - 3390 of 10000 in total
  1. Drug

    Fruquintinib

    go.drugbank.com/drugs/DB11679
    ApprovedInvestigational

    This approval is based on favorable results obtained from the FRESCO and FRESCO-2 trials, where an increase in overall survival rate was observed in both trials.[L48791] … [A262102,A262107] Indeed, oncogenic activation, loss of tumor suppressor function, and hypoxia, usually facilitated by cancer cells, are known to upregulate VEGF.

    Categories: Antineoplastic and Immunomodulating Agents
  2. Drug

    Protirelin

    go.drugbank.com/drugs/DB09421
    Approved

    It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary. … hypothyroidism and acromegaly.

    Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone Antagonists
  3. Drug

    Pregnenolone

    go.drugbank.com/drugs/DB02789
    ApprovedInvestigationalWithdrawn

    A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists
  4. Drug

    Tegafur-uracil

    go.drugbank.com/drugs/DB09327
    Approved

    It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd.[A32073] It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA. … Tegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4.

  5. Drug

    Thiohexam

    go.drugbank.com/drugs/DB14200
    Approved

    It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.

  6. Drug

    Methyclothiazide

    go.drugbank.com/drugs/DB00232
    ApprovedWithdrawn

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)

    Categories: methyclothiazide and potassium, Genito Urinary System and Sex HormonesProducts: Duretic 5mg
  7. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. … Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes vaccines.

    Categories: Antiseptics and Disinfectants
  8. Drug

    Zosuquidar

    go.drugbank.com/drugs/DB06191
    Investigational

    Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.

  9. Drug

    Diphenoxylate

    go.drugbank.com/drugs/DB01081
    ApprovedIllicitInvestigational

    This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug Administration (FDA) and the DEA in the United States when used in preparations. … Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity.

    Mixtures: Diphenoxylate Hydrochloride and Atropine Sulfate, Diphenoxylate Hcl and Atropine SulfateCategories: Alimentary Tract and Metabolism
  10. Drug

    Epicriptine

    go.drugbank.com/drugs/DB11275
    Approved

    Epicriptine differs from the alpha form on the position of one methyl group.[T195] To know more about the mixture please visit [DB01049]