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Aldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalthis amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125. … This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for
Products: PROLEUKIN POWDER FOR INFUSION 18 miu/vialGadoxetic acid
go.drugbank.com/drugs/DB08884ApprovedInvestigationalGadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.
Products: Primovist 0.25 mmol/ml Solution for injection, PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTIONTeprotumumab
go.drugbank.com/drugs/DB06343ApprovedInvestigationalwhich its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and was approved by the FDA in January 2020 for … Graves' Disease involving inflammation and tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive surgeries - teprotumumab is the first drug ever approved for
Synonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimerCategories: Insulin-like Growth Factor-1 Receptor InhibitorMethylnaltrexone
go.drugbank.com/drugs/DB06800ApprovedInvestigationalMethylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. ...
Categories: Drugs for Constipation, Peripheral Opioid Receptor AntagonistsProducts: Relistor Solution For Injection 12mg/0.6mLLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and, in doing so, prevents the formation of the 70S initiation complex which is essential for
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: ZYVOX SOLUTION FOR INFUSION 2 mg/ml, Prezolid 2mg/ml Solution for InfusionFomepizole
go.drugbank.com/drugs/DB01213ApprovedVet approvedFomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene ...
Products: Fomepizole for InjectionCocoa butter
go.drugbank.com/drugs/DB11086ApprovedStill, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products.
Products: Dermatitica Synergy for treatment of DermatitisTechnetium Tc-99m albumin colloid
go.drugbank.com/drugs/DB09447ApprovedInvestigationalWithdrawnProducts: Pulmolite, Kit for the Preparation of Technetium Tc99m Albumin AggregatedCefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalIt has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefuroxime Axetil For Oral Suspension, Hovid Cmaxid for Injection 1.5gSpectinomycin
go.drugbank.com/drugs/DB00919ApprovedVet approvedWithdrawnIt is active against gram-negative bacteria and used for the treatment of gonorrhea.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: TROBICIN FOR INJECTION 2 g/vial