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Mycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigationalMycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. … Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A6 Substrates with a Narrow Therapeutic IndexProducts: MYCOPHENOLATMOFET AL 250MG, MYCOPHENOLATMOFET AL 500MGParecoxib
go.drugbank.com/drugs/DB08439ApprovedInvestigationalParecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. … Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).
Products: PARECOXB parecoxib (as sodium) 40mg powder for solution for injectionNimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnNimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
Products: NIMESULIDE HEXAL AG, MESULID SUSPENSION AL 1 %Sulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawn[A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses.
Products: SULPIRID AL 50, SULPIRID AL 200Nizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Products: Axid ArMontelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationala generic and as a brand name product. … Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.
Products: Ag-montelukast, MONTELUKAST AL 4MGAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. … Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations
Mixtures: Ac and C Tab 1/8gr, Novo Ac and C 8mg TabProducts: Ag-asa EC, Ag-asa ChewPolyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Categories: Compounds used in a research, industrial, or household settingProducts: ALCOHOL POLIVINILICO AL 1.4%Cholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalStructurally, ergocalciferol differs from cholecalciferol in that it possesses a double bond between C22 and C23 and has an additional methyl group at C24 [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation
Mixtures: Vinate AZ, Am CapsProducts: Ag-vitamine D, COLECALCIFEROLO ABCCilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Categories: Compounds used in a research, industrial, or household settingProducts: CILOSTAZOL AL 50MG TAB, CILOSTAZOL AL 100MG TAB