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Displaying results 331 - 340 of 10000 in total
  1. Drug

    Conivaptan

    go.drugbank.com/drugs/DB00872
    Approved

    Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). … It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH).

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Vaprisol Dextrose In Plastic Container
  2. Drug

    Certolizumab pegol

    go.drugbank.com/drugs/DB08904
    ApprovedInvestigational

    [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019.[L5819] … done directly in bacterial hosts such as _E. coli_.

    Products: CIMZIA 200 MG ILO IN FER, CIMZIA 200MG ILO IN FER
  3. Drug

    Asparaginase Escherichia coli

    go.drugbank.com/drugs/DB00023
    ApprovedInvestigational

    Asparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999].

    Synonyms: Asparaginase II, L-AsnaseProducts: LEUNASE INJ., LEUNASE FOR INJECTION 10,000 iu/vial
  4. Drug

    Teicoplanin

    go.drugbank.com/drugs/DB06149
    ApprovedInvestigationalWithdrawn

    All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety. … Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4).

    Products: TEKOSIT 200 MG IM/IV LIYOFILIZE TOZ ICEREN 1 AMPUL, TEKOSIT 400 MG IM/IV LIYOFILIZE TOZ ICEREN 1 FLAKON
  5. Indication

    Ulcerative Colitis in Remission

    go.drugbank.com/conditions/DBCOND0050040
    Drugs: Mesalazine · Sulfasalazine
    Synonyms: Ulcerative Colitis in Remission, Ulcerative colitis in remission (disorder)
  6. Indication

    Accommodative component in esotropia

    go.drugbank.com/conditions/DBCOND0089181
    Drugs: Echothiophate
    Synonyms: Accommodative component in esotropia, Accommodative component in esotropia (disorder)
  7. Indication

    Ductal Carcinoma In Situ

    go.drugbank.com/conditions/DBCOND0037614
    Drugs: Tamoxifen
    Synonyms: Ductal Carcinoma In-situ, Ductal Carcinoma In Situ
  8. Drug

    Nitric Oxide

    go.drugbank.com/drugs/DB00435
    ApprovedInvestigational

    This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. … It is also a toxic air pollutant produced by automobile engines and power plants.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Stickstoff(II)-oxid, óxido de nitrógeno(II)
  9. Indication

    Endoscopic Diagnosis in Esophagus

    go.drugbank.com/conditions/DBCOND0084643
    Drugs: Ranitidine
    Synonyms: Endoscopic Diagnosis in Esophagus
  10. Indication

    Bleeding in invasive procedures

    go.drugbank.com/conditions/DBCOND0106041
    Drugs: Lusutrombopag
    Synonyms: Bleeding in invasive procedures