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Ulobetasol
go.drugbank.com/drugs/DB00596Approved[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses. … [L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Phenylbutazone
go.drugbank.com/drugs/DB00812ApprovedVet approvedWithdrawnAlthough phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this disease. (From AMA Drug Evaluations Annual, 1994, p1822)
Synonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedioneCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticTalniflumate
go.drugbank.com/drugs/DB09295InvestigationalPhase I trials with talniflumate for the treatment of cystic fibrosis and COPD were completed in August 2001, and phase II trials were performed in Ireland for the treatment of cystic fibrosis but this … research has now been discontinued [L1402, L1405].
Categories: Anti-Inflammatory Agents, Non-SteroidalAmrubicin
go.drugbank.com/drugs/DB06263InvestigationalSince January 2005, Amrubicin has been marketed by Nippon Kayaku, a Japanese pharmaceutical firm focused on oncology, which licensed Japanese marketing rights from Dainippon Sumitomo, the original developer … Pharmion licensed the rights to Amrubicin in November 2006. In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both SCLC and NSCLC.
Lemuteporfin
go.drugbank.com/drugs/DB04980InvestigationalLemuteporfin, under development by QLT Incorporated, is a benzoporphyrin-derived chlorin-like photosensitizer. It is intended for the treatment of beign prostatic hyperplasia.
Pirlindole
go.drugbank.com/drugs/DB09244ExperimentalThe antidepressant efficacy and safety of pirlindole have been demonstrated in numerous studies and, supported by many years of clinical experience in the treatment of depression. … Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug.
Synonyms: 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazoleCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSerotonin
go.drugbank.com/drugs/DB08839InvestigationalNutraceuticalNot evaluated by the FDA, homeopathic product.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMK-4965
go.drugbank.com/drugs/DB08460ExperimentalMK-4965 is an HIV-1 reverse transcriptase inhibitor.
MK-886
go.drugbank.com/drugs/DB16739ExperimentalMK-886 is an experimental inhibitor of leukotriene synthesis.
rsPSMA Vaccine
go.drugbank.com/drugs/DB06361ApprovedWithdrawnan ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on