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Cortisone acetate
go.drugbank.com/drugs/DB01380ApprovedInvestigational[A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory
Tazemetostat
go.drugbank.com/drugs/DB12887ApprovedInvestigationalTazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
Desirudin
go.drugbank.com/drugs/DB11095ApprovedWithdrawnIt has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients.
Lactitol
go.drugbank.com/drugs/DB12942Approved[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.[L11803] … [A190912] Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in
Carbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnThe compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued. … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Methoxamine
go.drugbank.com/drugs/DB00723ApprovedInvestigationalWithdrawnIt has little if any direct effect on the central nervous system.
Remibrutinib
go.drugbank.com/drugs/DB16852ApprovedInvestigationalThe FDA approved remibrutinib on September 30, 2025 as the only oral, targeted treatment for chronic spontaneous urticaria.
Quinaprilat
go.drugbank.com/drugs/DB14217ExperimentalThe active metabolite of the prodrug [quinapril].
Categories: Agents Acting on the Renin-Angiotensin SystemPerindoprilat
go.drugbank.com/drugs/DB14213ExperimentalThe active metabolite of the prodrug [Perindopril].
Categories: Agents Acting on the Renin-Angiotensin SystemTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigational[A189717] Tafamidis is structurally similar to diflusinal.[A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]