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Disintegrin and metalloproteinase domain-containing protein 10
go.drugbank.com/bio_entities/BE0002404TargetHumansTransmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins, including adhesion proteins, growth factor precursors and cytokines being essential for development and tissue homeostasis (PubMe...
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 10Synonyms: ADAM 10Sialic acid-binding Ig-like lectin 10
go.drugbank.com/bio_entities/BE0018431TargetHumansPutative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with ...
Polypeptides: Sialic acid-binding Ig-like lectin 10Synonyms: Siglec-10Cyclopentolate
go.drugbank.com/drugs/DB00979ApprovedA parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Synonyms: 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate, 2-(dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetateMixtures: Mydriatic-3Protokylol
go.drugbank.com/drugs/DB06814ApprovedVet approvedProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
Categories: Heterocyclic Compounds, 1-Ring, Epinephrine and similarsProducts: OPTİCAİNE %0.5 GÖZ DAMLASI, ÇÖZELTİ 5 MLBromazepam
go.drugbank.com/drugs/DB01558ApprovedIllicitIt is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: BROMAZEPAM FARMA 1, BROMAZEPAM 6 1A PHARMAAzilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigationalLowering blood pressure is associated with a reduced risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. … As hypertension is a major risk factor for cardiovascular disease,[A7354] early management of hypertension has several implications on patients' survival rate and quality of life in the future.
Mixtures: EDARBYCLOR (TABLETS) 40 MG/12.5 MG, EDARBYCLOR (TABLETS) 40 MG/12.5 MGCategories: Heterocyclic Compounds, 1-Ring, Angiotensin II Type 1 Receptor BlockersAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
Mixtures: EMEND® 80 MG/125 MG, EMEND® 80 MG/125 MGCategories: Neurokinin 1 Antagonists, Heterocyclic Compounds, 1-RingOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigationalOzanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. … [A189336] In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard
Mixtures: ZEPOSIA 7-Day Starter Pack, ZEPOSIA 7-Day Starter PackCategories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsExemestane
go.drugbank.com/drugs/DB00990ApprovedInvestigationalExemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 6-methyleneandrosta-1,4-diene-3,17-dioneDegarelix
go.drugbank.com/drugs/DB06699ApprovedInvestigationalDegarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. … Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: FIRMAGON Powder and Solvent for Solution for Injection 120 mg, FIRMAGON Powder and Solvent for Solution for Injection 80 mg