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Nerandomilast
go.drugbank.com/drugs/DB18237ApprovedInvestigational[L54126] On October 7, 2025, nerandomilast was approved as the first new treatment for idiopathic pulmonary fibrosis in more than a decade. … FDA approved nerandomilast tablets for the treatment of progressive pulmonary fibrosis (PPF) in adults.
Xanomeline
go.drugbank.com/drugs/DB15357ApprovedInvestigational[A264514] Xanomeline is a muscarinic agonist that was approved for the treatment of schizophrenia by the FDA in September 2024, becoming the first approved treatment for schizophrenia to target muscarinic … [A264509] Advances in pre-clinical research and findings in clinical trials have led to a resurgence of interest in the cognition-enhancing potential of muscarinic agonists in schizophrenia, as it was
Pargyline
go.drugbank.com/drugs/DB01626ApprovedPargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePleconaril
go.drugbank.com/drugs/DB05105InvestigationalPleconaril is an antiviral drug from _viral capsid inhibitor_ class, manufactured by _Schering-Plough_ and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic … Food and Drug Administration (FDA) due to the fact that it has been found to induce CYP3A enzyme activity, therefore increasing the risk for serious drug interactions.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseRotavirus vaccine
go.drugbank.com/drugs/DB10276ApprovedInvestigational[L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. … [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain.[Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.[L1117]
Categories: Antiinfectives for Systemic UseHexafluronium
go.drugbank.com/drugs/DB00941ApprovedHexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. … It is known to bind and block the activity of plasma cholinesterases.
Synonyms: Hexafluorenium ionAlbiglutide
go.drugbank.com/drugs/DB09043ApprovedInvestigationalWithdrawnIt is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide was approved on April 15, 2014 by the FDA. … Albiglutide is a glucagon-like peptide-1 agonist (GLP-1) biologic drug indicated in the treatment of type 2 diabetes. It is marketed under the brands Eperzan and Tanzeum by GSK (GlaxoSmithKline).
Categories: Drugs Used in DiabetesHydrogenated soybean oil
go.drugbank.com/drugs/DB11302ApprovedAccording to the FDA, hydrogenated soybean oil is generally recognized as safe (GRAS) food substance. … It may be found in cosmetics and personal care products as an emollient or skin conditioning agent.
Phenprocoumon
go.drugbank.com/drugs/DB00946ApprovedInvestigationalWithdrawnCoumarin derivative that acts as a long-acting oral anticoagulant.
Categories: Vitamin K Inhibitors, Vitamin K AntagonistsChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnChlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Synonyms: -PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINE, ETHENAMINE, 2-(1-(4-CHLOROPHENYL)-1-PHENYLETHOXY)-N,N-DIMETHYL-Categories: Antihistamines for Topical Use, Antihistamines for Systemic Use