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Bromazepam
go.drugbank.com/drugs/DB01558ApprovedIllicitOne of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. … It is a intermediate-acting benzodiazepine.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: BROMAZEPAM N&P, LEXOTAN® TABLETAS 6 MG.Isoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and cardiac output, without vasoconstriction … [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline].
Categories: Adrenergic beta-2 Receptor Agonists, Compounds used in a research, industrial, or household settingSynonyms: N-isopropyl-β-dihydroxyphenyl-β-hydroxyethylamine, 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanolVilobelimab
go.drugbank.com/drugs/DB16416ApprovedInvestigationalVilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of human C5a with high affinity. … The drug is not yet fully approved for this condition.[L45849]
Synonyms: IFX-1Daclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnThis withdrawal was concurrent to the European Medicines Agency announcement of a recall owing to 12 worldwide reports of serious inflammatory brain disorders associated with the use of Zinbryta (daclizumab … Despite being approved for use, Zinbryta (daclizumab)'s complex pre-existing safety profile consisting of its restricted availability through a Risk Evaluation and Mitigation Strategy program [L1738] and
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyShark liver oil
go.drugbank.com/drugs/DB11088ApprovedHowever the major component is considered to be squalene, which may range up to 90% of the shark oil, depending on the species. … Shark oil is extracted from the livers of sharks, which can account for up to 25% of their total body weight.
Mixtures: PREPARATION H OINTMENT, PREPARATION H SUPPOSITORIESPemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalPemigatinib is marketed under the brand name Pemazyre, and it is available as oral tablets.[L13050] … [L13068] Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy.
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalIt was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir. … One major use of valacyclovir is the treatment of genital herpes episodes or outbreaks.
Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanineCeftobiprole
go.drugbank.com/drugs/DB04918ApprovedWithdrawnThe EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European … Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially as the prodrug [ceftobiprole medocaril].
Categories: Heterocyclic Compounds, 2-RingGonadorelin
go.drugbank.com/drugs/DB00644ApprovedInvestigationalVet approvedGnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary. … Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis.
Mixtures: -pws Liq-kit IV Sc, -pws Liq-kit Sc IVProducts: LH-RH FERRING 0,1 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADETEquine Botulinum Neurotoxin A Immune FAB2
go.drugbank.com/drugs/DB13900ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in adults and pediatric patients. … Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype A.
Synonyms: Botulinum Neurotoxin A immune FAB2 (equine), BOTULINUM NEUROTOXIN A IMMUNE FAB2, EQUINE