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Displaying results 3411 - 3420 of 9333 in total
  1. Drug

    Oxyphenbutazone

    go.drugbank.com/drugs/DB03585
    ApprovedWithdrawn

    Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.

  2. Drug

    Perindoprilat

    go.drugbank.com/drugs/DB14213
    Experimental

    The active metabolite of the prodrug [Perindopril].

    Categories: Agents Acting on the Renin-Angiotensin System
  3. Drug

    Imlunestrant

    go.drugbank.com/drugs/DB19043
    ApprovedInvestigational

    [L54046] Imlunestrant works by antagonizing ER transcriptional activity and, by forming an unstable drug-receptor complex, promotes ER degradation via the ubiquitin-proteasome pathway. … The FDA approved imlunestrant on September 25, 2025 [L54051] as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-mutated advanced or metastatic breast cancer with

  4. Drug

    Tositumomab

    go.drugbank.com/drugs/DB00081
    ApprovedWithdrawn

    It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).

  5. Drug

    Suvorexant

    go.drugbank.com/drugs/DB09034
    ApprovedInvestigational

    It has been approved for the treatment of insomnia.

  6. Drug

    Quinaprilat

    go.drugbank.com/drugs/DB14217
    Experimental

    The active metabolite of the prodrug [quinapril].

    Categories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    Prednisolone

    go.drugbank.com/drugs/DB00860
    ApprovedInvestigationalVet approved

    Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.

    Synonyms: Predniso(lo)neProducts: SCHERISOLONA® TABLETAS DE 5 MG
  8. Drug

    Teglarinad chloride

    go.drugbank.com/drugs/DB05217
    Investigational

    Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis. … GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity.

  9. Drug

    Pregnenolone

    go.drugbank.com/drugs/DB02789
    ApprovedInvestigationalWithdrawn

    Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.

  10. Drug

    Midomafetamine

    go.drugbank.com/drugs/DB01454
    IllicitInvestigational

    It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome