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Displaying results 3421 - 3430 of 10000 in total
  1. Drug

    Oxaprotiline

    go.drugbank.com/drugs/DB09307
    Experimental

    Dextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A). … Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A).

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  2. Drug

    Bordetella pertussis pertactin antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10992
    ApprovedInvestigational

    Mixtures: INFANRIX (TM) - IPV
  3. Indication

    Myalgia

    go.drugbank.com/conditions/DBCOND0002210
    Drugs: (+)-menthol · (S)-camphor · 2-(l-menthoxy)ethanol · Acetaminophen · Acetylsalicylic acid · Borneol +28 more
  4. Drug

    Lovotibeglogene autotemcel

    go.drugbank.com/drugs/DB18680
    ApprovedInvestigational

    [A262736,L49256] On December 8, 2023, lovotibeglogene autotemcel was approved by the FDA under the brand name Lyfgenia for the treatment of sickle cell disease (SCD) in patients ages 12 and older who … Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene.

  5. Drug

    Dicoumarol

    go.drugbank.com/drugs/DB00266
    Approved

    Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. … In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.

    Categories: 4-Hydroxycoumarins, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexSynonyms: 3,3'-methylenebis(4-hydroxy-2H-1-benzopyran-2-one), bis(4-hydroxycoumarin-3-yl)methane
  6. Drug

    Rolapitant

    go.drugbank.com/drugs/DB09291
    ApprovedInvestigational

    By blocking Substance P from interacting with NK-1 receptors in the gut and the central nervous system, rolapitant prevents late-phase CINV. … Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults.

    Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 Antagonists
  7. Drug

    Pozelimab

    go.drugbank.com/drugs/DB15218
    ApprovedInvestigational

    [L47880] The pathophysiology of this disease is mainly attributed to the deficiency of the CD55 protein, which is the main regulator of the complement cascade.[A261105,A261110,A261115]. … [A261120] Pozelimab is a human, monoclonal immunoglobulin G4<sup>P</sup> antibody against the terminal complement protein C5.

  8. Drug

    Aspergillus fumigatus

    go.drugbank.com/drugs/DB10425
    Approved

    Aspergillus fumigatus is a fungus which can provoke allergic reactions. Aspergillus fumigatus extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  9. Drug

    Cochliobolus sativus

    go.drugbank.com/drugs/DB10433
    Approved

    Cochliobolus sativus is a fungus which can provoke allergic reactions. Cochliobolus sativus extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  10. Drug

    Daraxonrasib

    go.drugbank.com/drugs/DB22308
    ApprovedInvestigational

    [L64039] It is a RAS(ON) tri-complex inhibitor that binds cyclophilin A and targets the active, GTP-bound ("ON") state of RAS, suppressing signaling of both wild-type and mutant RAS across the most common … Daraxonrasib is an orally administered, multi-selective inhibitor of the RAS GTPase family used to treat metastatic pancreatic adenocarcinoma.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates