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Displaying results 3421 - 3430 of 10000 in total
  1. Drug

    Vayarin

    go.drugbank.com/drugs/DB09328
    Approved

    Vayarin is currently available only by prescription in the USA [L1502]. This drug has also been used for management of hypertriglyceridemia [L1503].

  2. Drug

    SO-101

    go.drugbank.com/drugs/DB05345
    Experimental

    Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day. … SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia.

  3. Drug

    Itraconazole

    go.drugbank.com/drugs/DB01167
    ApprovedInvestigational

    First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each posses...

    Products: Z-FIN
  4. Drug

    Patupilone

    go.drugbank.com/drugs/DB03010
    Investigational

    Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.

  5. Target

    Flavohemoprotein

    go.drugbank.com/bio_entities/BE0002917
    TargetEscherichia coli (strain K12)

    Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various

    Synonyms: NOD, NO oxygenase
  6. Drug

    Tetrahydrocannabivarin

    go.drugbank.com/drugs/DB11755
    Investigational

    Δ9-THC is currently available in several synthetic forms, including [Dronabinol], while purified or isolated THCV is not approved for any medical uses and is not available as any marketed products. … Although THCV possesses an almost identical structure to Δ9-THC (varying only by the length of its lipophilic alkyl chain), it has different molecular targets and pharmacological profile [A32972].

  7. Drug

    Quinine

    go.drugbank.com/drugs/DB00468
    ApprovedInvestigational

    The mechanisms of its antimalarial effects are not well understood. … Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels.

    Categories: Analgesics, Non-Narcotic
  8. Drug

    Folitixorin calcium

    go.drugbank.com/drugs/DB05308
    Investigational

    ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of the widely used cancer chemotherapy, 5-fluorouracil (5-FU). CoFactor use with 5-FU is being evaluated in cli...

  9. Drug

    Embusartan

    go.drugbank.com/drugs/DB19949
    Experimental

    The usage of the INN stem '-sartan' in the name indicates that Embusartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). … Embusartan has a monoisotopic molecular weight of 461.19 Da.

  10. Drug

    Pomisartan

    go.drugbank.com/drugs/DB20188
    Experimental

    The usage of the INN stem '-sartan' in the name indicates that Pomisartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). … Pomisartan has a monoisotopic molecular weight of 490.24 Da.