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Displaying results 3421 - 3430 of 10000 in total

Drug
CYT-6091
go.drugbank.com/drugs/DB05991
Experimental
It was under investagtion in clinical trials NCT00356980 and NCT00436410 for the treatment of various cancers. … CYT-6091 (Aurimune) is an investigational small molecule made up of recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated polyethylene glycol bound to the surface of 27 nm colloidal gold
Categories: Compounds used in a research, industrial, or household setting
Drug
Oxymorphone
go.drugbank.com/drugs/DB01192
ApprovedVet approved
It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092). … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity.
Categories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
Drug
Trospium
go.drugbank.com/drugs/DB00209
ApprovedInvestigational
[L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007.[L6211] … Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably.
Categories: Drugs for Urinary Frequency and Incontinence, Drugs for Functional Gastrointestinal DisordersProducts: Sanctura XR
Drug
Cyclopentolate
go.drugbank.com/drugs/DB00979
Approved
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Products: Ak-pentolate
Drug
Rotavirus vaccine
go.drugbank.com/drugs/DB10276
ApprovedInvestigational
[L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. … [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain.[Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.[L1117]
Categories: Antiinfectives for Systemic Use
Drug
Rindopepimut
go.drugbank.com/drugs/DB05374
Investigational
The US FDA granted it Breakthrough Therapy Designation for glioblastoma in Feb 2015. … Rindopepimut (CDX-110) is an injectable peptide cancer vaccine which targets a mutant protein called EGFRvIII present in about 25% to 30% of glioblastoma cases.
Drug
Beeswax
go.drugbank.com/drugs/DB11600
Approved
Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions. … It is also used as a coating in the manufacture of modified-release oral preparations
Drug
Hexocyclium
go.drugbank.com/drugs/DB06787
Approved
Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. … Proton pump inhibitors like [DB00338] and opiate anti-diarrheal agents like [DB00836] have largely replaced the use of anti-muscarinics in the treatment of gastric ulcers and diarrhea due to their more
Categories: Drugs for Functional Gastrointestinal Disorders
Drug
Benzhydrocodone
go.drugbank.com/drugs/DB15465
Approved
[A182177] Benzhydrocodone is indicated for use in the short-term management of pain. … Benzhydrocodone is a benzylic prodrug of hydrocodone.[L4894] It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse.
Drug
Dihydroergocornine
go.drugbank.com/drugs/DB11273
Approved
[T190] It is found as one of the components in the ergoloid mesylate mixture. To know more about this mixture please refer to [DB01049] … [A32964] The formation of dihydroergocornine implies the hydrogenation of the double bonds in the lysergic acid.
Categories: Heterocyclic Compounds with 4 or More Rings