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Displaying results 3441 - 3450 of 10000 in total
  1. Drug

    Mitiglinide

    go.drugbank.com/drugs/DB01252
    Investigational

    It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.

    Categories: Drugs Used in Diabetes
  2. Drug

    Tesmilifene

    go.drugbank.com/drugs/DB04905
    Investigational

    Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast

    Synonyms: N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine
  3. Drug

    Chlorphenesin

    go.drugbank.com/drugs/DB00856
    Approved

  4. Drug

    Prednisolone sodium metazoate

    go.drugbank.com/drugs/DB05340
    Investigational

    ATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery system that releases the medication only in the colon. … Colal-Pred is being studied for use in ulcerative colitis.

  5. Drug

    Thioredoxin

    go.drugbank.com/drugs/DB11298
    Approved

    It plays an essential role as an antioxidant in neutralizing food allergens and redox signalling. Allergens containing disulfide bonds are inactivated when reduced by thioredoxin. … Thioredoxin is a small dithiol protein and specific reductant for major allergenic proteins present in foods from animal and plant products.

  6. Drug

    Brecanavir

    go.drugbank.com/drugs/DB04887
    Investigational

    In July 2006, Vertex indicated that it expected GSK to initiate phase III trials of the drug in 2007. … Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV.

  7. Drug

    Methyl undecenoyl leucinate

    go.drugbank.com/drugs/DB11272
    Approved

    Methyl undecenoyl leucinate is an active ingredient in whitening creams. … It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.

  8. Drug

    Phenacetin

    go.drugbank.com/drugs/DB03783
    ApprovedWithdrawn

    Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).

  9. Drug

    Kinetin

    go.drugbank.com/drugs/DB11336
    Approved

    While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents. … It was shown to naturally exist in DNA of organisms including humans and various plants.

  10. Drug

    Imetelstat

    go.drugbank.com/drugs/DB14909
    ApprovedInvestigational

    [A187838] Imetelstat received FDA approval in June 2024 for use in certain patients with MDS who have transfusion-dependent anemia and are unable to use ESAs.[L50883,L50888] … Imetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase.