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Eravacycline
go.drugbank.com/drugs/DB12329ApprovedInvestigationalIt was first approved by the FDA on August 27, 2018 [L4540].
Mezlocillin
go.drugbank.com/drugs/DB00948ApprovedIt has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Ciclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Votucalis
go.drugbank.com/drugs/DB05032InvestigationalrEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Chlorotrianisene
go.drugbank.com/drugs/DB00269ApprovedWithdrawnA powerful synthetic, non-steroidal estrogen. [PubChem]
International brands: Tace FNRofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. … On September 30, 2004, Merck voluntarily withdrew rofecoxib from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use.
Dextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnDextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. … Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States.
Mixtures: Darvocet-N 50, Darvocet-N 100Products: Darvon-NDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approved[L42880] It is a second-generation tetracycline that was first discovered in 1967.[A19429] Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines.
Voacamine
go.drugbank.com/drugs/DB04877ExperimentalVoacamine is also under investigation for use in modulating multidrug-resistance in tumor cells. … Voacamine is an alkaloid isolated from the bark of the _Pescheria fuchsiae folia_ tree. It is an antimalarial drug approved for use in several African countries.
Depreotide
go.drugbank.com/drugs/DB11628ApprovedWithdrawnDepreotide is an ingredient in the EMA-withdrawn product NeoSpect.