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Efbemalenograstim alfa
go.drugbank.com/drugs/DB18704ApprovedInvestigationalEfbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration … This approval was contingent on positive results observed in two pivotal Phase 3 Studies GC-627-04 and GC-627-05 in the US and Europe respectively.[L48887]
Synonyms: Rh g-csf fc fusion protein f-627, Recombinant dimeric g-csf fusion protein f627TG-1042
go.drugbank.com/drugs/DB18435InvestigationalTG-1042 (formerly known as ASN-002) is a recombinant adenovirus carrying the cDNA coding sequence for the human interferon gamma gene.
AMG 424
go.drugbank.com/drugs/DB17357InvestigationalAMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Synonyms: AMG-424, Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38Vimseltinib
go.drugbank.com/drugs/DB17520ApprovedInvestigational[L52230] It is highly selective, with a >500-fold selectivity for CSF1R over its nearest off-target kinase. … [A265035] It is intended to provide a safer alternative to [pexidartinib], a previously approved CSF1R inhibitor associated with significant liver toxicity - the greater selectivity of vimseltinib results
Synonyms: 2-(isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)pyrimidin-4(3h)-one, 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4-pyridinyl)oxy)-2-pyridinyl)-4(3h)-pyrimidinoneDementia With Lewy Body Disease
go.drugbank.com/conditions/DBCOND0077924Synonyms: Late onset dementia due to Lewy body disease (disorder)Head Injury
go.drugbank.com/conditions/DBCOND0028168Drugs: CerebrolysinSynonyms: [X]Injuries to the head (disorder)Hospital-Acquired Pneumonia
go.drugbank.com/conditions/DBCOND0038730Synonyms: Pneumonia due to bacteria NOS (disorder)Lemborexant
go.drugbank.com/drugs/DB11951ApprovedInvestigational[L10863] Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits, but rather an inability to … [suvorexant]) act to counteract inappropriate wakefulness.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: DAYVIGO FILM-COATED TABLET 5MG, Dayvigo 5mg Film coated tabletAG-24322
go.drugbank.com/drugs/DB13035InvestigationalAG-024322 has been used in trials studying the treatment of Neoplasms and Lymphoma, Non-Hodgkin.
MK-0482
go.drugbank.com/drugs/DB17453InvestigationalMK-0482 is a novel humanized IgG4 monoclonal antibody targeting the immunoglobulin-like transcript (ILT) 3.