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Pexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigationalIn clinical trials, pexidartinib was shown to promote improvements in patient symptoms and functional outcomes in TGCT. … [A182243] Pexidartinib is available in oral formulations and it is commonly marketed as Turalio.[L7901]
3,3'-diindolylmethane
go.drugbank.com/drugs/DB11875InvestigationalDiindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.
Categories: Compounds used in a research, industrial, or household settingZongertinib
go.drugbank.com/drugs/DB18762ApprovedInvestigational[L53873,A274363] On August 8, 2025, the US FDA granted accelerated approval to zongertinib for the treatment of advanced forms of non-small cell lung cancer (NSCLC) with HER2 tyrosine kinase domain
Bird pepper
go.drugbank.com/drugs/DB14262ApprovedBird pepper is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Rice bran
go.drugbank.com/drugs/DB14361ApprovedRice bran is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Milk thistle
go.drugbank.com/drugs/DB14375ApprovedInvestigationalMilk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Amdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnIt is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Aztreonam
go.drugbank.com/drugs/DB00355ApprovedInvestigationalIt is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Pramiracetam
go.drugbank.com/drugs/DB13247ApprovedPramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression [L5470]. … It was also previously approved in the United States with orphan drug designation [L1469].
Amylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnElsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French word 'fourneau' as 'stove' in English [L1882]. … Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately [L1882].