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Displaying results 3481 - 3490 of 10000 in total
  1. Drug

    Amibegron

    go.drugbank.com/drugs/DB05395
    Investigational

    Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.

    Categories: Adrenergic beta-3 Receptor Agonists
  2. Drug

    Doripenem

    go.drugbank.com/drugs/DB06211
    ApprovedWithdrawn

    In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates … , resulting in a premature termination of the trial.

  3. Target

    Beta-ketoacyl-[acyl-carrier-protein] synthase III

    go.drugbank.com/bio_entities/BE0003868
    TargetEnterococcus faecalis (strain ATCC 700802 / V583)

    Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role...

    Synonyms: KAS III
  4. Drug

    Ropeginterferon alfa-2b

    go.drugbank.com/drugs/DB15119
    ApprovedInvestigational

    Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for … [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life.

    Categories: Interferon Type I
  5. Drug

    Aluminium

    go.drugbank.com/drugs/DB01370
    ApprovedInvestigationalWithdrawn

    A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.

  6. Drug

    Sodium bisulfite

    go.drugbank.com/drugs/DB14015
    ApprovedWithdrawn

    Sodium bisulfite has been used externally for parasitic skin diseases and as a gastrointestinal antiseptic.

    Mixtures: Nephramine Liq IV, LIBAVIT-K 20 MG AMPUL, 5 ADETCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction. … PDE5 inhibitors, such as vardenafil, inhibit the degradation of cGMP and allow increased blood flow into the penis, resulting in an erection.[A258303,L45563,L45568].

    Categories: Drugs Used in Erectile Dysfunction
  8. Drug

    Peginterferon alfa-2a

    go.drugbank.com/drugs/DB00008
    ApprovedInvestigational

    Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].

    Categories: Interferon Type I, Compounds used in a research, industrial, or household setting
  9. Target

    Non-secretory ribonuclease

    go.drugbank.com/bio_entities/BE0001306
    TargetHumans

    This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities

    Synonyms: RNase UpI-2
  10. Drug

    Griseofulvin

    go.drugbank.com/drugs/DB00400
    ApprovedVet approved

    An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.