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L-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalas neuroprotective disease-modifying effect of the DL-form of N-acetylleucine, after which animal studies showed that the L-enantiomer (i.e. levacetylleucine) has potential clinical benefits compared to
Spinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad has also been experimented for use in cats for treatment of flea infestations, and has also been experimented for use against the KS1 Ctenocephalides felis flea strain infesting dogs, in addition to
Corynebacterium diphtheriae
go.drugbank.com/drugs/DB09877ApprovedInvestigationalThe vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Tertomotide
go.drugbank.com/drugs/DB12747InvestigationalIt is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells. It is being developed by Pharmexa A/S. … Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma).
Tranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalA propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and p...
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMethopterin
go.drugbank.com/drugs/DB16620InvestigationalMethopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.[A229843]
Polihexanide
go.drugbank.com/drugs/DB12277ApprovedInvestigational[L53003] It was initially approved in August of 2024, and is the first and only approved therapy to treat patients with _Acanthamoeba_ keratitis. [L53143]
MBO7133
go.drugbank.com/drugs/DB04999ExperimentalMB07133 uses our HepDirect technology to target a prodrug form of araCMP specifically to the liver. … AraC's anti-cancer activity is associated with its ability to be converted to its biologically active form, araCTP.
gamma-Hydroxybutyric acid
go.drugbank.com/drugs/DB01440ApprovedIllicitInvestigationalHowever, it is important to note that GHB is a designated Orphan drug (in 1985).